著者

HIROKI SHIMURA SHINICHI SUZUKI TOSHIHIKO FUKUSHIMA SANAE MIDORIKAWA SATORU SUZUKI NAOMI HAYASHIDA MISA IMAIZUMI NORIYUKI OKUBO YASUSHI ASARI TAKESHI NIGAWARA FUMIHIKO FURUYA KAZUHIKO KOTANI SHIGEYUKI NAKAJI AKIRA OTSURU TAKASHI AKAMIZU MASAFUMI KITAOKA NOBORU TAKAMURA MASAFUMI ABE HITOSHI OHTO NOBUYUKI TANIGUCHI SHUNICHI YAMASHITA

出版者

福島医学会

雑誌

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)

巻号頁・発行日

pp.2014-28, (Released:2014-12-20)

参考文献数

33

被引用文献数

4

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Contents1. Introduction2. Thyroid ultrasound examination in Fukushima3. Thyroid ultrasound findings in children in three Japanese prefectures4. Prevalence of thyroid nodular lesions in children and adolescents 4.1 Thyroid cyst 4.2 Thyroid nodule 4.3 Thyroid cancer5. SummaryConflict of interestReference

著者

HIROKI SHIMURA SHINICHI SUZUKI TOSHIHIKO FUKUSHIMA SANAE MIDORIKAWA SATORU SUZUKI NAOMI HAYASHIDA MISA IMAIZUMI NORIYUKI OKUBO YASUSHI ASARI TAKESHI NIGAWARA FUMIHIKO FURUYA KAZUHIKO KOTANI SHIGEYUKI NAKAJI AKIRA OTSURU TAKASHI AKAMIZU MASAFUMI KITAOKA NOBORU TAKAMURA MASAFUMI ABE HITOSHI OHTO NOBUYUKI TANIGUCHI SHUNICHI YAMASHITA

出版者

THE FUKUSHIMA SOCIETY OF MEDICAL SCIENCE

雑誌

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)

巻号頁・発行日

vol.60, no.2, pp.196-202, 2014 (Released:2015-02-26)

参考文献数

33

被引用文献数

4

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Contents1. Introduction2. Thyroid ultrasound examination in Fukushima3. Thyroid ultrasound findings in children in three Japanese prefectures4. Prevalence of thyroid nodular lesions in children and adolescents 4.1 Thyroid cyst 4.2 Thyroid nodule 4.3 Thyroid cancer5. SummaryConflict of interestReference

著者

Tasuku Okui Yutaka Matsuyama Shigeyuki Nakaji

出版者

The Biometric Society of Japan

雑誌

計量生物学 (ISSN:09184430)

巻号頁・発行日

vol.39, no.2, pp.55-84, 2019-01-31 (Released:2019-05-11)

参考文献数

59

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Nowadays, many methods that employ the 16S ribosomal RNA gene (16S rRNA sequencing data) have been proposed for the analysis of gut microbial compositional data. 16S rRNA sequencing data is statistically multivariate count data. When multivariate data analysis methods are used for association analysis with a disease, 16S rRNA sequencing data is generally normalized before analysis models are fitted, because the total sequence read counts of the subjects are different. However, proper methods for normalization have not yet been discussed or proposed. Rarefying is one such normalization method that equals the total counts of subjects by subsampling a certain amount of counts from each subject. It was thought that if rarefying were combined with ensemble learning, performance improvement could be achieved. Then, we proposed an association analysis method by combining rarefying with ensemble learning and evaluated its performance by simulation experiment using several multivariate data analysis methods. The proposed method showed superior performance compared with other analysis methods, with regard to the identification ability of response-associated variables and the classification ability of a response variable. We also used each evaluated method to analyze the gut microbial data of Japanese people, and then compared these results.

著者

AKIHIRO MUNAKATA SHIGEYUKI NAKAJI HIDEKI TAKAMI HITOSHI NAKAJIMA SATORU IWANE SEIKI TUCHIDA

出版者

Tohoku University Medical Press

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.171, no.2, pp.145-151, 1993 (Released:2006-08-31)

参考文献数

33

被引用文献数

36 48

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MUNAKATA, A., NAKAJI, S., TAKAMI, H., NAKAJIMA, H., IWANE, S. and TUCHIDA, S. Epidemiological Evaluation of Colonic Diverticulosis and Dietary Fiber in Japan. Tohoku J. Exp. Med., 1993, 171(2), 145-151 - The incidence of colonic diverticulosis was examined in 5 hospitals geographically isolated from each other in Japan during the period between mid '70s and 1986. The incidence rapidly increased in all hospitals from 3.5-9.0% in mid '70s to 8.4-23.2% in 1986. The ratio of right-sided type colonic diverticulosis was approximately 70-80% in each hospital and the ratio did not fluctuate significantly during the period. Birth cohort analysis revealed that although the incidence of right-sided diverticula had increased with aging, in groups born in more recent decades right-sided diverticula appeared in younger age than other groups. It was suggested that environmental factors rather than congenital factors may cause the increase of the incidence of right-sided colon diverticula.