著者

MITSUAKI TSUNAKAWA OSAMU TENMYO KOJI TOMITA NOBUAKI NARUSE CHIKAKO KOTAKE TAKEO MIYAKI MASATAKA KONISHI TOSHIKAZU OKI

出版者

JAPAN ANTIBIOTICS RESEARCH ASSOCIATION

雑誌

The Journal of Antibiotics (ISSN:00218820)

巻号頁・発行日

vol.45, no.2, pp.180-188, 1992-02-25 (Released:2006-04-19)

参考文献数

14

被引用文献数

31 33

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A strain of Amycolatopsis orientalis No. Q427-8 (ATCC 53884) was found to produce a complex of new antiviral antibiotics, quartromicin which consisted of at least six components A1, A2, A3, D1, D2 and D3. Structural studies suggested that they are a novel type of molecules unrelated to any known antibiotics. Each component of quartromicin exhibited antiviral activity against herpes simplex virus type 1, influenza virus type A and human immunodeficiency virus.