著者

菊川 峰志

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.61, no.1, pp.012-015, 2021 (Released:2021-01-29)

参考文献数

12

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Cl–-pump rhodopsin is the second discovered microbial rhodopsin and functions as light-driven Cl– pump. The physiological significance of the Cl– pump has not been fully resolved. However, its functional mechanism has been studied as a model system of anion transporters. In this review, the variation and functional mechanisms of Cl–-pump rhodopsins were summarized. After 2014, novel Cl–-pump groups were discovered in marine and terrestrial bacteria and were revealed to have unique characteristics. The most recently identified protein has close similarity with the H+-pump rhodopsin and begins to pump H+ outwardly by only a single amino acid replacement.