著者
冨田 寛 田中 真琴 生井 明浩
出版者
日本微量元素学会
雑誌
Biomedical Research on Trace Elements (ISSN:0916717X)
巻号頁・発行日
vol.18, no.1, pp.54-62, 2007 (Released:2007-05-29)
参考文献数
22
被引用文献数
7

1. In Japan, patients with taste disorder as a primary symptom of zinc deficiency are increasing.2. The incidence of taste disorder due to diet (insufficient intake of zinc) is especially high. The serum zinc value in patients with taste disorder due to diet was 20μg/dl (in many cases mean value is 60-79μg/dl )lower than the healthy group, but the half cases remained in more than 80μg/dl.3. The efficacy of oral administration of zinc in patients with taste disorder due to diet did not correlate with the zinc value before this therapy, but about 85%.4. Increasing rate of serum zinc values after the oral zinc therapy in patients with taste disorder due to diet was significantly high more than the placebo group. Lower serum zinc values in the patients were more effective. Correlate with the amount of oral administration of zinc.5. We would like to propose 80μg/dl as the diagnosis value(cutoff value) of zinc deficiency, referring to the above results and the conclusion of the Yokoi's study(Association between plasma zinc concentrations and zinc kinetic parameters in premenopausal women).

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味覚障害には15に及ぶ原因があり、その中で亜鉛欠乏と関係あるものは、 •食事性亜鉛欠乏症 •亜鉛キレート能のある治療薬剤の服用例(220 種類もある) •亜鉛の吸収・排泄に関係がある全身疾患(慢性消化器疾患、肝硬変、ネフローゼ、糖尿病、甲状腺機能低下症など) https://t.co/ml3O6EcVtH
血清亜鉛のカットオフ値は80、 日内変動で午後採血なら10はかわると。カットオフ値以上でも、臨床症状があれば積極的に補充を。と。 ほんそれ。 https://t.co/NxfYXqGyea
エビデンスに基づいた血清亜鉛値による亜鉛欠乏症の診断基準値 https://t.co/tUCGgiYOIP

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