著者
Hongzhou Lu
出版者
International Research and Cooperation Association for Bio & Socio-Sciences Advancement
雑誌
BioScience Trends (ISSN:18817815)
巻号頁・発行日
vol.14, no.1, pp.69-71, 2020-02-29 (Released:2020-03-16)
参考文献数
18
被引用文献数
252

As of January 22, 2020, a total of 571 cases of the 2019-new coronavirus (2019-nCoV) have been reported in 25 provinces (districts and cities) in China. At present, there is no vaccine or antiviral treatment for human and animal coronavirus, so that identifying the drug treatment options as soon as possible is critical for the response to the 2019-nCoV outbreak. Three general methods, which include existing broad-spectrum antiviral drugs using standard assays, screening of a chemical library containing many existing compounds or databases, and the redevelopment of new specific drugs based on the genome and biophysical understanding of individual coronaviruses, are used to discover the potential antiviral treatment of human pathogen coronavirus. Lopinavir /Ritonavir, Nucleoside analogues, Neuraminidase inhibitors, Remdesivir, peptide (EK1), abidol, RNA synthesis inhibitors (such as TDF, 3TC), anti-inflammatory drugs (such as hormones and other molecules), Chinese traditional medicine, such ShuFengJieDu Capsules and Lianhuaqingwen Capsule, could be the drug treatment options for 2019-nCoV. However, the efficacy and safety of these drugs for 2019- nCoV still need to be further confirmed by clinical experiments.

言及状況

外部データベース (DOI)

Twitter (14 users, 14 posts, 23 favorites)

Interferon alpha 2b: Chinese guidelines for COVID-19 have used 5 million IU IFN-α 2b, twice per day, nebulized in 2mL sterile water. https://t.co/4J1XNvK4ko https://t.co/H5UAyU4sde https://t.co/F0FFg625id https://t.co/g6j2kRe8VE https://t.co/vlPswac11E
@Stevens_AK There have been many trials. The Podcast needs to be updated. 571 patients https://t.co/DYvOIBuBdh https://t.co/HnXAC7g2Ck
Para médicos y especialistas. Drug treatment options for the 2019-new coronavirus (2019-nCoV) https://t.co/69tYEzyBee
https://t.co/YSKz3d99ya https://t.co/YSKz3d99ya
Drug treatment options for the 2019-new coronavirus (2019-nCoV) https://t.co/ZugkREdprb

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