著者
Rie Hayashi Hiroyasu Iso Kazumasa Yamagishi Hiroshi Yatsuya Isao Saito Yoshihiro Kokubo Ehab S. Eshak Norie Sawada Shoichiro Tsugane for the Japan Public Health Center-Based (JPHC) Prospective Study Group
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-18-0842, (Released:2019-03-06)
参考文献数
43
被引用文献数
1

Background: Evidence from prospective cohort studies regarding the relationship between working hours and risk of cardiovascular disease is limited Methods and Results: The Japan Public Health Center-Based Prospective Study Cohort II involved 15,277 men aged 40–59 years at the baseline survey in 1993. Respondents were followed up until 2012. During the median 20 years of follow up (257,229 person-years), we observed 212 cases of acute myocardial infarction and 745 stroke events. Cox proportional hazards models adjusted for sociodemographic factors, cardiovascular risk factors, and occupation showed that multivariable-adjusted hazard ratios (HRs) associated with overtime work of ≥11h/day were: 1.63 (95% confidence interval [CI] 1.01–2.63) for acute myocardial infarction and 0.83 (95% CI 0.60–1.13) for total stroke, as compared with the reference group (working 7 to <9 h/day). In the multivariable model, increased risk of acute myocardial infarction associated with overtime work of ≥11 h/day was more evident among salaried employees (HR 2.11, 95% CI 1.03–4.35) and men aged 50–59 years (HR 2.60, 95% CI 1.42–4.77). Conclusions: Among middle-aged Japanese men, working overtime is associated with a higher risk of acute myocardial infarction.

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長時間労働者…確かに心血管疾患が多い印象。 https://t.co/XIDTEO8e5k
Working Hours and Risk of Acute Myocardial Infarction and Stroke Among Middle-Aged Japanese Men ― The Japan Public… https://t.co/RXuaHZYV5D
1日の労働時間が7-9時間群と比して,11時間以上群は急性心筋梗塞リスクが1.63倍増加し,中でも勤務者では2.11倍,追跡開始年齢50歳以上では2.6倍増加する.本邦15277例20年追跡コホート研究(Circ J 2019 M… https://t.co/q5Idz8Mhr5
【日本、40-59歳男性15277名、20年 [中央値] 観察:212例でMI、脳卒中は745例。1日「7-9時間」労働に比べ、「11時間以上」で、MI補正後HRは1.63 [95%CI 1.01-2.63]。一方、脳卒中は0.8… https://t.co/lvXH9HnbIf

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