著者
Yasuhiro Ito Takumi Kudo Minoru Kihara Yuuki Takamura Kaoru Kobayashi Akihiro Miya Akira Miyauchi
出版者
(社)日本内分泌学会
雑誌
Endocrine Journal (ISSN:09188959)
巻号頁・発行日
vol.59, no.10, pp.895-901, 2012 (Released:2012-10-31)
参考文献数
8
被引用文献数
3 11

In this study, we investigated the difference in lymph node-recurrence free survival (LN-RFS), distant recurrence-free survival (DRFS), and cause-specific survival (CSS) between patients with papillary thyroid carcinoma (PTC) in the entire group (Group I) and those with lymph node- and distant-recurrence-free survival (DFS) for 5 years after initial surgery (Group II). The LN-RFS of patients with all risk classifications in Group II was significantly better than that of those in Group I. The LN-RFS of intermediate-risk patients in Group II did not differ from that of low-risk patients in Group I, but LN-RFS of high-risk patients in Group II was significantly poorer than intermediate- and low-risk patients in Group I. DRFS and CSS of Group II patients did not significantly differ from those of Group I patients in the same risk classification. DRFS and CSS of high-risk patients in Group II were significantly poorer than those of intermediate- and low-risk patients in Group I, and those of intermediate-risk patients in Group II were also significantly poorer than those of low-risk patients in Group I. Taken together, the lymph node recurrence rate, but not distant recurrence and carcinoma death rates, of patients in all classifications significantly improved after DFS for 5 years. However, careful follow-up for lymph node recurrence of high-risk patients and for distant recurrence of intermediate- and high-risk patients is necessary thereafter.

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甲状腺癌の早期発見のメリットを指摘した論文も存在 http://t.co/8d2aPitqyo https://t.co/Iq4NmiXUBM  リンパ節転移していない甲状腺癌のほうが予後がいい https://t.co/YqQP2eTQlD
.@keiki22 @yoshi022 この論文https://t.co/YqQP2elcbz のグラフのように、進行していると再発率が高くなるようなんですよ。再発は患者にとって負担が大きいと聞きました。
隈病院でのPTC全年齢5784例のDFS率の分析。https://t.co/YqQP2eCfdz 再発の死亡率も出ている。オカルト癌を見つけだしたほうがいいかどうかも、議論が分かれるのではないか。
隈病院の論文 1. https://t.co/STLbEoRAsb リンパ節転移は20歳以下が多い(死亡例は1/104) 隅病院の論文 2. リンパ節転移と予後の関係の分析 (8-87歳) https://t.co/YqQP2eCfdz
隈病院の論文。無料公開なのがうれしい。 Improvement of lymph node recurrence rate.. https://t.co/YqQP2eCfdz リンパ節転移と予後の関係の分析 (8-87歳)

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