著者
Ken Kanazawa Shogo Suzuki Tatsuro Inaba Shinichiro Koga Koichiro Kuwabara
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.1405-22, (Released:2023-04-07)
参考文献数
14
被引用文献数
1

Biliary pseudolithiasis is a ceftriaxone (CTRX)-induced complication, but the risk in cases of elderly type 1 diabetes mellitus (T1DM) is unclear. Case 1: A 78-year-old woman with T1DM complicated by diabetic autonomic neuropathy was admitted with pneumonia and treated with CTRX. On day 8, biliary pseudolithiasis and cholecystitis were observed. Case 2: an 80-year-old woman with T1DM was suspected of having a urinary tract infection and treated with CTRX. After a week, she developed asymptomatic biliary pseudolithiasis with gastroparesis. CTRX-associated biliary pseudolithiasis was thus noted in these cases of elderly T1DM. CTRX should be cautiously administered, especially in elderly T1DM patients with diabetic autonomic neuropathy.

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【高齢1型DMでCTRXによる胆道結石に注意(Intern Med)】 胆道結石はセフトリアキソン(CTRX)の有害事象として知られているが、eGFR<60でハザード比8.14(1.05-63.0)、女性でハザード比5.35 (1.17-24.5)と高い。 CTRX使うときには注意。 https://t.co/seVNXcqOHK https://t.co/3umwRPMrwS

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