著者
Kaori Sakurada Tsuneo Konta Masafumi Watanabe Kenichi Ishizawa Yoshiyuki Ueno Hidetoshi Yamashita Takamasa Kayama
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20180249, (Released:2019-04-06)
参考文献数
23

Background: Positive and negative psychological factors are associated with mortality and cardiovascular disease. This study prospectively investigated associations between daily frequency of laughter, and mortality and cardiovascular disease in a community-based population.Methods: This study included 17,152 subjects ≥40 years old who participated in an annual health check in Yamagata Prefecture. Self-reported daily frequency of laughter was grouped into 3 categories (≥1/week; ≥1/month but <1/week; <1/month). Associations between daily frequency of laughter and increase in all-cause mortality and cardiovascular disease incidence were determined using Cox proportional hazards modeling.Results: During follow-up (median, 5.4 years), 257 subjects died and 138 subjects experienced cardiovascular events. Kaplan-Meier analysis revealed that all-cause mortality and cardiovascular disease incidence were significantly higher among subjects with a low frequency of laughter (log-rank P<0.01). Cox proportional hazard model analysis adjusted for age, gender, hypertension, smoking, and alcohol drinking status showed that risk of all-cause mortality was significantly higher in subjects who laughed <1/month than in subjects who laughed ≥1/week (hazard ratio (HR) 1.95, 95% confidence interval (CI), 1.16-3.09). Similarly, risk of cardiovascular events was higher in subjects who laughed ≥1/month but < 1/week than in subjects who laughed ≥1/week (HR 1.62, 95% CI, 1.07-2.40).Conclusion: Daily frequency of laughter represents an independent risk factor for all-cause mortality and cardiovascular disease in a Japanese general population.

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外部データベース (DOI)

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あまり笑わない人は早死にしやすい。山形県の健康診断に参加した40歳以上の男女17,152人に「笑う頻度」を尋ねて、中央値で5.4年にわたって追跡すると、月に1回未満しか笑わない人は週に1回以上笑う人より総死亡リスクが95%、週に1… https://t.co/BOz86bETkb
J-STAGE Articles - Associations of frequency of laughter with risk of all-cause mortality and cardiovascular diseas… https://t.co/K6k4dJrVEv
Associations of Frequency of #Laughter w/ Risk of All-Cause #Mortality & #Cardiovascular #Disease Incidence in a Ge… https://t.co/lvMe2LWEcY
#laughter usually is associated with a longer life https://t.co/M7nL61DuIM (hat tip: @CharlesMBrenner) #humour #health

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