- The Society of Practical Otolaryngology
- 耳鼻咽喉科臨床 (ISSN:00326313)
- vol.102, no.11, pp.945-949, 2009 (Released:2011-06-09)
The efficacy of the common practice in Japan of recommending gargling to prevent post-tonsillectomy infection and to reduce throat soreness remains to be scientifically and quantitatively confirmed. In an attempt to remedy this, we had 108 subjects—48 men and 60 women aged 17 to 79 years (mean: 33.8 years)—gargle with povidone-iodine (PI) or sodium guaiazulen-3-sulfonate (AZ) following bilateral tonsillectomy. We measured the clinical effects on a pain scale and pain-medication score for comparison between the two groups. Results indicated by the medication score and pain scale demonstrated that gargling with AZ significantly reduced pain compared to gargling with PI, especially right after surgery. AZ also showed an antipyretic effect, suggesting that gargling with AZ is superior to PI as a post operative gargle.