- JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY
- ORAL THERAPEUTICS AND PHARMACOLOGY (ISSN:02881012)
- vol.17, no.1, pp.18-22, 1998-04-01 (Released:2010-06-08)
This study was conducted to asses the clinial efficacy of Sai-boku-to (Kanpo) in comparison to minor tranquilizer with vitamin B complex medication for the treatment of glossodynia.Either Sai-boku-to (7.5g per day) of minor tranquilizer (Diazepam) 6mg per day with vitamine B complex medication for three months was P. O. administered to 104 cases. The clinical examination was carried out in order to evaluate the subjective symptoms such as pain, heat sensation, and unpleasent feeling in comcomitant treatment of glossodynia.After three-month administration the success rates were 75.8 %, 87.1 %, and 88.7 % in the Sai-boku-to medication group and 73.8 %, 71.4 %, 69.0 % in the minor tranquilizer medication group. The Sai-boku-to medication group was significantry superior to the minor tranquilizer medication group. The side effect of the sleepiness was found in 13 cases in the minor tranquilizer medication group. On the contrary, a mild signs and symptoms of digestive discomfort was noted in three cases in the Sai-boku-to medication group.These results suggested that Sai-boku-to was a clinically useful drug for the treatment of glossodvnia.