著者
Harumi Okuyama Naoki Ohara Kenjiro Tatematsu Shinya Fuma Tomoyuki Nonogaki Kazuyo Yamada Yuko Ichikawa Daisuke Miyazawa Yuko Yasui Seijiro Honma
出版者
The Japanese Society of Toxicology
雑誌
The Journal of Toxicological Sciences (ISSN:03881350)
巻号頁・発行日
vol.35, no.5, pp.743-747, 2010-10-01 (Released:2010-10-01)
参考文献数
25
被引用文献数
5 6 5

Canola and some other types of oil unusually shorten the survival of stroke-prone spontaneously hypertensive rats (SHRSP), compared with soybean oil, perilla oil and animal fats. Since differential effects of canola and soybean oil on steroid hormone metabolism were suggested by a preliminary DNA microarray analysis as a reason for this, the steroid hormone levels in the serum and tissues of SHRSP fed different oils were investigated. The testosterone levels in the serum and the testes were found to be significantly lower in the canola oil group than in the soybean oil group, while no significant differences were detected in the corticosterone and estradiol levels in tissues. In a second experiment, it was found that hydrogenated soybean oil, with a survival-shortening activity comparable to that of canola oil, also decreased the testosterone level in testes to a similar degree. The testosterone-lowering activity of canola and hydrogenated soybean oil observed in SHRSP was considered in relation to other factors possibly affecting the physiology of SHRSP.

言及状況

外部データベース (DOI)

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@thierrysouccar @drnickgreiner @MorganPfiffner Just go right ahead https://t.co/6bKi47sKCz
@GidMK Study here. If you are up to it. https://t.co/aG0pasu54j Do you think this non seed oil preference better?
Řepkový olej snižuje testosteron :O potřebujete další důvod proč ho vyhodit? Působí pro-zanětlivě, obsahuje transma… https://t.co/yyDbwihgTM
@Kamuela https://t.co/zllsHcRBsc
Canola oil lowers test. 40-50% in rats&presumably as well in men. This stuff is in most normie food. (((#Resist))) https://t.co/tupi13RzJm
Canola oil lowers testosterone (a lot, 40-50%) in rats, even compared to soybean oil https://t.co/zllsHcRBsc

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