著者
Junwoo BAE Mahmoud SOLIMAN Hyunwoo KIM Seongwoo KANG Woosun KIM Soomin AHN Kyoungoh CHO Jihye CHOI Suhee KIM Jinho PARK Sangki KIM Yoonjung DO Jaegyu YOO Dohyeon YU
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
(Released:2017-09-02)

Hydroxyethyl starches (HES) are commonly used synthetic colloidal solution in veterinary medicine. Despite of possible adverse effect to kidney injury in human, there is no report about nephrotoxic effects of HES in dogs. HES was administered to a Golden retriever (4-year-old, intact male) with ascites in order to increase plasma osmolality. Initially, the dog was mild azotemic, however, kidney function was rapidly deteriorated after several days of HES administration. Finally, histopathological examination revealed remarkable osmotic nephrosis. In the case reported herein, acute kidney injury was remarkably developed after HES administration. Clinical and histopathologic findings of acute kidney injury support nephrotoxic effects of HES to a dog.

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Rapid exacerbation of renal function after administration of #hydroxyethyl starch in a #dog https://t.co/OFJvrOgmMs #veterinary
Rapid exacerbation of renal function after administration of #hydroxyethyl starch in a #dog https://t.co/OFJvrOgmMs #veterinary
rapid exacerbation of renal function after administration of hydroxyethyl #starch in a dog https://t.co/VYSRBFUu0m https://t.co/HeROW5oQkT

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