著者
山本 (前田) 万里 永井 寛 江間 かおり 神田 えみ 岡田 典久 安江 正明
出版者
公益社団法人 日本食品科学工学会
雑誌
日本食品科学工学会誌 (ISSN:1341027X)
巻号頁・発行日
vol.52, no.12, pp.584-593, 2005 (Released:2007-04-13)
参考文献数
31
被引用文献数
8 8

A double-blind clinical study was carried out on subjects with Japanese cedar pollinosis for the evaluation of the effects and safety of ‘Benifuuki’ green tea, which contains epigallocatechin-3-O-(3-O-methyl)-gallate (O-methylated catechin), and a combination of ‘Benifuuki’ green tea and ginger extract, with ‘Yabukita’ green tea as a placebo. First, the effect of the combination of ‘Benifuuki’ green tea and various vegetable extracts on cytokine production inhibition was investigated using mast cells ; the simultaneous use of ‘Benifuuki’ green tea and ginger extract was found to suppress cytokine (TNF-α or MIPI-α) production to a remarkable extent. Subjects were given 1.5 g of ‘Benifuuki’ green tea, ‘Benifuuki’ green tea containing 30 mg of ginger extract, or ‘Yabukita’ green tea with water twice every day for 13 weeks. As cedar pollen scattering increased, the severity of pollinosis symptoms among the groups was observed to increase in the following order : placebo group>’Benifuuki’ group>’Benifuuki’ and ginger group. Eleven weeks after the beginning of treatment, during the most severe cedar pollen scattering period, symptoms of runny nose and itchy eyes were significantly relieved among the ‘Benifuuki’ group compared with the placebo group (p<0.05). In the ‘Benifuuki’ and ginger group, runny nose, itchy eyes and nose symptom scores were significantly reduced at the eleventh week, and nasal congestion, sore throat and nose symptom medication scores were significantly reduced at the thirteenth week compared with the placebo group. Among all test groups, hematological examination, general biochemical examination, determination of total IgG, CMV antibody titer, and serum iron content, and interviews throughout the intake period found no changes related to clinical problems. These results suggest that intake of ‘Benifuuki’ green tea over one month is useful in reducing some of the symptoms of Japanese cedar pollinosis, and did not affect normal immune response in subjects with Japanese cedar-pollinosis. It was also found that the addition of ginger extract enhanced the effect of ‘Benifuuki’ green tea.

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@ma_03Lilly 論文読んでみましたが、短期的な有意差はそれほどなく、長期的に飲むといいというような感じでした 来年のために飲む?という様になる気もします…。 また、現段階で研究中の内容ですし、はっきりとした効果は…と言うのが個人的見解です 花粉少しでもマシになりますように… https://t.co/BJwV0YPyKz
https://t.co/yMGBntH6YG さらにはこんな話も 「べにふうき」の強い抗肥満効果は,EGCGよりも吸収性および血中滞留性に優れたEGCG3″Meを始めとするメチル化カテキンが特異的に含まれているためと考えられた.」 https://t.co/PBG6hJcvTk

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