著者
木島 孝夫 高崎 みどり 小塚 睦夫 徳田 春邦
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.114, no.4, pp.248-256, 1994-04-25 (Released:2008-05-30)
参考文献数
27
被引用文献数
1 2

To search for possible anti-tumor promoters, we carried out a primary screening of fourteen kampo prescriptions utilizing their possible inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation which is induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). In these prescriptions, shouseiryu-to exhibited the most significant inhibitory effect on the EBV-EA activation. Furtheremore, two-stage carcinogenesis of mouse skin tumors induced by 7, 12-dimethylbenz [α] anthracene (DMBA) and TPA, and mouse pulmonary tumors induced by 4-nitroquinoline-N-oxide (4NQO) and glycerol were strongly inhibited by shouseiryu-to.

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漢方方剤の抗発癌プロモーター作用(第2報)小青龍湯によるマウス皮膚及び肺発癌プロモーター抑制効果【1994】 小青龍湯に極めて強いEpstein−Barr Virus抑制効果を認めた。 https://t.co/iQHKpSpJbh

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