著者
KATSUHIKO OHNUMA KENICHI AOKI AND TAKERU AKAZAWA
出版者
The Anthropological Society of Nippon
雑誌
Anthropological Science (ISSN:09187960)
巻号頁・発行日
vol.105, no.3, pp.159-168, 1997 (Released:2010-10-21)
参考文献数
12
被引用文献数
17 19

We describe a series of preliminary experiments undertaken to investi-gate the relationship between complicated tool-making and the presence or absence of language in its communicative role. The experiments involved teaching two groups of university students how to make Levallois flakes by either verbal or non-verbal demonstration. The rates and mean times of acquisition of the Levallois technique and of successful flake production were compared. They did not differ significantly between the two groups. From these results, we infer that spoken language was not indispensable for Levallois flake production in the Middle Palaeolithic.
著者
柴山 太
出版者
一般財団法人 日本国際政治学会
雑誌
国際政治 (ISSN:04542215)
巻号頁・発行日
vol.2008, no.154, pp.154_46-154_61, 2008

This article presents an analytic sketch of the Hattori Group's thoughts and behavior in 1947&ndash;1952. This group, headed by ex-Colonel of Imperial Japanese Army HATTORI Takushiro, consisted of ex-members of General Staff of Imperial Japanese Army, and it sought for Japan's rearmament and its military independence from U. S. strategic influence. The group, after its establishment in 1947, intended to realize a Japanese rearmament, following the successful model of German Army's rearmament in the 1920s and 1930s. Its members admired Generals Hans von Seeckt and Paul von Hindenburg as spiritual mentors. In spite of the outbreak of the Cold War, the group never changed its original nature of Prussian-style staff officers, characterized by conviction of military rule over politics, militaristic mind, and pride of staff officers. The group vigorously waged lobbying activities for its future enrollment in a new Japanese Army and a reintroduction of prewarstyle military and governmental systems. Moreover, this group intended to revive prewar army dominance in politics, and, if possible, it desired to regain prewar continental resources and interests in Korea and China.<br>Despite the Hattori Group's posture of aiming at Japanese military autonomy from the U. S. auspice, it had been financially and politically dependent on Major General Charles Willoughby, Chief of G-2 (Intelligence), GHQ, the Far East Command. It was the most significant discrepancy, though the group members persuaded themselves that they simply used his support as a temporary measure. Since Willoughby's influence inside GHQ was gradually waning away, even more so after the dismissal of General Douglas MacArthur, Supreme Commander of the Allied Powers, the group had to find another political patron. On the one hand, the group developed its political tie with ex-General SHIMOMURA Sadamu, who was once Prime Minister YOSHIDA Shigeru's military adviser. On the other hand, it endeavored to win a support from HATOYAMA Ichiro.<br>Prime Minister Yoshida, however, denied the Hattori Group's participation in Japanese National Police Reserve, forerunner of Ground Self-Defense Force, Japan. The group continued to advocate the reintroduction of Prussian-style professional army. This vision, no doubt, contradicted Yoshida's vision of founding an Anglo-American style democratic army in Japan. Before Yoshida's unshakable refusal, Hattori and his colleagues became so desperate to consider a coup d'&eacute;tat, aiming at an assassination of Yoshida and an introduction of the Hatoyama cabinet. The group eventually abandoned the coup plot, but it continued to influence over Japanese politics.
著者
成瀬 厚
出版者
公益社団法人 日本地理学会
雑誌
E-journal GEO (ISSN:18808107)
巻号頁・発行日
vol.8, no.1, pp.78-95, 2013 (Released:2013-09-13)
参考文献数
34

日本国内の航空旅客数は減少傾向にあり,国や地方自治体が管理する多くの空港は赤字経営が続いている.さまざまな空港利用促進事業が行われるなかで,近年は空港に愛称や通称をつける動きがある.本稿はこの動向を中心に地方空港の運営状態を地理学的に考察することを目的とする.本稿では,地理学における場所論と地名研究,場所のプロモーション研究を参照することで,空港を一つの場所としてとらえている.国内の政治的階層,地理的スケールにおいて中間の位置を占める地方自治体は,下位の地域住民から意見を集約し,決定した名称を上位の国家から公認を取得する形で公式化する.空港名の愛称化の目的は日本全体に対する地方空港の認知度や親しみやすさの向上であり,それに付随して空港で開催されるイベントの目的は地域住民に対するイメージの向上であると同時に空港施設の多目的利用化であるといえる.
著者
川村 喜一郎 金松 敏也 山田 泰広
出版者
一般社団法人 日本地質学会
雑誌
地質学雑誌 (ISSN:00167630)
巻号頁・発行日
vol.123, no.12, pp.999-1014, 2017-12-15 (Released:2018-03-28)
参考文献数
142

本論では,海底地すべりの一般的な特徴,短期および長期の発生メカニズム,海底地すべりによる海洋ハザードについて概説する.海底地すべりは,その形状から,一般的に滑落ドメイン,移動ドメイン,末端ドメインの3つの領域に区画される.滑落ドメインでは開口亀裂,移動ドメインでは剪断変形に起因する非対称変形構造が見られる.末端ドメインでは,圧力隆起部によって特徴づけられる.滑り面は粘土層であると推測されるが,南海トラフで報告されているように非条件下では,砂層も滑り面となる可能性がある.短期的な発生メカニズムは,斜面における荷重の急激な増加や間隙水圧の急激な上昇など,地震に最も関連している.長期的な発生メカニズムは,気候変動によるメタンハイドレートの分解とそれに伴う間隙水圧の増加,長期的な間隙水圧の増加,海山の沈み込み/衝突による地盤の変形,火山活動による斜面勾配の急斜化などがある.

15 15 15 5 OA 口絵

著者
クレインス フレデリック
出版者
国際日本文化研究センター
雑誌
日本研究 = NIHON KENKYŪ
巻号頁・発行日
vol.56, 2017-10-20
著者
大岡 伸通
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.138, no.9, pp.1135-1143, 2018-09-01 (Released:2018-09-01)
参考文献数
28

Protein knockdown technologies based on small molecules are attracting considerable attention in the pharmaceutical industry as a strategy for novel drug discovery. We and others have developed such compounds, designated as Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs), proteolysis-targeting chimeras (PROTACs), and Degronimids, which induce selective degradation of target proteins. These compounds contain two different ligands, specific for an ubiquitin E3 ligase and for a target protein, respectively, connected by a linker. SNIPERs, PROTACs, and Degronimids are designed to cross-link E3 ligase and the target protein to induce polyubiquitylation and proteasomal degradation of the target protein within cells. To recruit the von Hippel-Lindau (VHL) E3 ligase complex and the cereblon (CRBN) E3 ligase complex, a VHL inhibitor and a thalidomide derivative have been integrated into PROTAC and Degronimid constructs, respectively. Similarly, an IAP antagonist has been incorporated into SNIPERs to recruit cellular inhibitor of apoptosis protein 1 (cIAP1) or X-linked inhibitor of apoptosis protein (XIAP) E3 ligase. To date, a range of such compounds have been developed, allowing selective degradation of a variety of proteins, including estrogen receptor α (ERα), oncogenic kinase BCR-ABL, and epigenetic regulator bromodomain-containing protein 4 (BRD4). Some compounds have also demonstrated ability to degrade target proteins in vivo, suggesting that this technology is feasible for use in novel drug development.

37 17 4 4 OA 前進する朝鮮

出版者
朝鮮総督府情報課
巻号頁・発行日
1942

10 5 4 4 OA 我が観たる満鮮

著者
中野正剛 著
出版者
政教社
巻号頁・発行日
1915