著者

鈴木 竜太

出版者

The Japanese Association of Administrative Science

雑誌

経営行動科学 (ISSN:09145206)

巻号頁・発行日

vol.30, no.3, pp.173-175, 2018 (Released:2018-07-31)

著者

吉岡 翼 小野村 一人

出版者

日本甲殻類学会

雑誌

CANCER (ISSN:09181989)

巻号頁・発行日

vol.26, pp.13-15, 2017-08-01 (Released:2017-09-30)

参考文献数

13

著者

小口 太一 大西 真理 近川 幸恵 児玉 貴志 鈴木 えみり 笠原 正輝 穐山 浩 手島 玲子 布藤 聡 日野 明寛 古井 聡 橘田 和美

出版者

公益社団法人 日本食品衛生学会

雑誌

食品衛生学雑誌 (ISSN:00156426)

巻号頁・発行日

vol.50, no.1, pp.41-46, 2009-02-25 (Released:2009-03-26)

参考文献数

5

被引用文献数

2 14

---

食品・飼料としての利用を目的とした遺伝子組換えテンサイ品種が開発されている.本研究では,テンサイを原料とした加工食品を遺伝子組換え食品の検査の対象にすべきか評価するため,テンサイ糖製品におけるDNA残存の有無を調査した.複数のテンサイ内在性遺伝子配列を標的としたPCR分析の結果,テンサイに含まれるDNAは製糖過程の早い段階で分解され,テンサイ糖製品中から分析可能な質および量のDNAは回収できなかった.

著者

三村 均

出版者

日本イオン交換学会

雑誌

日本イオン交換学会誌 (ISSN:0915860X)

巻号頁・発行日

vol.25, no.3, pp.45-51, 2014 (Released:2014-09-20)

参考文献数

13

被引用文献数

1 2

---

東日本大震災で発生した大津波は,福島第一原子力発電所を襲い,原子力発電の安全神話を覆すレベル 7 の原子力事故を引き起こした。国内最悪の事故はいまだ収束に至らず,発電所周辺住民は,震災と原子力事故という二重の苦しみの生活を強いられている。事故対策を進める上で,50 万トン規模の高汚染水が大きな障害となっている。海水が混入した高汚染水の浄化,特に Cs の選択的除染に対しては,無機イオン交換体充填吸着塔による循環注水冷却システムが稼動しており,冷温停止が達成されているが,運転システムの高度化や二次固体廃棄物の安全管理および処分が課題となっている。ここでは,ゼオライトを主体とした Cs および Sr 選択性吸着剤の吸着特性および固化特性を比較評価するとともに,吸着剤の高機能化の試みを紹介する。わが国に豊富に産出する天然産ゼオライトは,Cs に高い選択性を有すると共に,高温での Cs ガスのトラッピング機能および安定固化を実現できる自己焼結機能など優れた特性を有しており,高汚染水の処理および処分において今後重要な役割を果たすものと期待できる。

著者

Reboul Julien Furukawa Shuhei Horike Nao Tsotsalas Manuel Hirai Kenji Uehara Hiromitsu Kondo Mio Louvain Nicolas Sakata Osami Kitagawa Susumu

出版者

Nature Publishing Group

雑誌

Nature materials (ISSN:14761122)

巻号頁・発行日

vol.11, no.8, pp.717-723, 2012-06-24

被引用文献数

352 26

---

化石化を逆転させ、多孔性メゾ構造体の形をデザイン : 高速分離でバイオエタノール精製などの効率化へ.京都大学プレスリリース.2012-06-25.

著者

Miyaura Norio Yamada Kinji Suzuki Akira

出版者

Pergamon Press

雑誌

Tetrahedron Letters (ISSN:00404039)

巻号頁・発行日

vol.20, no.36, pp.3437-3440, 1979

被引用文献数

1797

---

The representative (E)-1-alkenyldisiamylboranes and (E)-1-alkenyl-1,3,2-benzodioxaboroles readily obtainable Image hydroboration of 1-alkynes react with 1-alkenyl halides or 1-alkynyl halides in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium and base to give corresponding conjugated (E)-dienes or (E)-enynes with high regio- and stereospecificity in good yields, respectively.

著者

豊田 秀樹 川端 一光 中村 健太郎 片平 秀貴

出版者

日本行動計量学会

雑誌

行動計量学 (ISSN:03855481)

巻号頁・発行日

vol.34, no.1, pp.101-110, 2007 (Released:2007-05-30)

参考文献数

15

被引用文献数

1 1 1

---

This study proposes the adoption of a neural network as an alternative to logistic regression analysis, which is conventionally used to estimate the propensity score (Rosenbaum & Rubin, 1983). Moreover, covariates that are frequently obscured are presented.Considering the response pattern to a mail survey by random sampling as a criterion, we examined how is the response pattern to a Web survey by purposive selection rectified using the propensity score. The propensity score was estimated using the subjects' demographic variables as covariates.The results of adopting a neural network were compared with those of the logistic regression analysis. As a result, the accuracy of bias reduction by the threelayer neural networks was found to be greater than that by the logistic regression analysis.In addition, detailed contents of the covariates were presented, and a decision tree was produced to examine the influence of covariates on allocation of the subjects to survey forms.

著者

Tadachika OKI Satoshi TAOKA Toshiya MASHIMA Toshimasa WATANABE

出版者

一般社団法人 電子情報通信学会

雑誌

IEICE Transactions on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E95.D, no.3, pp.769-777, 2012-03-01 (Released:2012-03-01)

参考文献数

15

被引用文献数

1

---

The k-edge-connectivity augmentation problem with bipartition constraints (kECABP, for short) is defined by “Given an undirected graph G=(V,E) and a bipartition π={VB,VW} of V with VB∩VW=∅, find an edge set Ef of minimum cardinality, consisting of edges that connect VB and VW, such that G'=(V,E∪Ef) is k-edge-connected.” The problem has applications for security of statistical data stored in a cross tabulated table, and so on. In this paper we propose a fast algorithm for finding an optimal solution to (σ+1)ECABP in O(|V||E|+|V2|log |V|) time when G is σ-edge-connected (σ > 0), and show that the problem can be solved in linear time if σ ∈ {1,2}.

著者

Kotaro BESSHO Kenji DATE Masahiro HAYASHI Akio IKEDA Takahito IMAI Hidekazu INOUE Yukihiro KUMAGAI Takuya MIYAKAWA Hidehiko MURATA Tomoo OHNO Arata OKUYAMA Ryo OYAMA Yukio SASAKI Yoshio SHIMAZU Kazuki SHIMOJI Yasuhiko SUMIDA Masuo SUZUKI Hidetaka TANIGUCHI Hiroaki TSUCHIYAMA Daisaku UESAWA Hironobu YOKOTA Ryo YOSHIDA

出版者

Meteorological Society of Japan

雑誌

気象集誌. 第2輯 (ISSN:00261165)

巻号頁・発行日

vol.94, no.2, pp.151-183, 2016 (Released:2016-04-28)

参考文献数

66

被引用文献数

143 871

---

Himawari-8/9—a new generation of Japanese geostationary meteorological satellites-carry state-of-the-art optical sensors with significantly higher radiometric, spectral, and spatial resolution than those previously available in the geostationary orbit. They have 16 observation bands, and their spatial resolution is 0.5 or 1 km for visible and near-infrared bands and 2 km for infrared bands. These advantages, when combined with shortened revisit times (around 10 min for Full Disk and 2.5 min for sectored regions), provide new levels of capacity for the identification and tracking of rapidly changing weather phenomena and for the derivation of quantitative products. For example, fundamental cloud product is retrieved from observation data of Himawari-8 operationally. Based on the fundamental cloud product, Clear Sky Radiance and Atmospheric Motion Vector are processed for numerical weather prediction, and volcanic ash product and Aeolian dust product are created for disaster watching and environmental monitoring. Imageries from the satellites are distributed and disseminated to users via multiple paths, including Internet cloud services and communication satellite services.

著者

大槻 マミ太郎 照井 正 小澤 明 森田 明理 佐野 栄紀 髙橋 英俊 小宮根 真弓 江藤 隆史 鳥居 秀嗣 朝比奈 昭彦 根本 治 中川 秀己

出版者

公益社団法人 日本皮膚科学会

雑誌

日本皮膚科学会雑誌 (ISSN:0021499X)

巻号頁・発行日

vol.121, no.8, pp.1561-1572, 2011-07-20 (Released:2014-11-13)

---

Clinical use of TNFα (tumor necrosis factor α) inhibitors, adalimumab and infliximab, for psoriasis began in January 2010 when an additional indication for this disease was approved. In January 2011, an interleukin-12/23 p40 (IL-12/23 p40) inhibitor, ustekinumab, was newly approved as the third biologic agent with an indication for psoriasis. All of these biologic agents are expected to exhibit excellent efficacy against not only psoriasis but also psoriatic arthritis, and to contribute to the improvement of quality of life (QOL) of psoriatic patients. At the same time, however, they require safety measures to prevent adverse drug reactions such as serious infections. We therefore decided to prepare this Guideline/Safety Manual for the Use of Biologic Agents in Psoriasis (The 2011 Version) by revising that for the use of TNFα Inhibitors prepared by the Biologics Review Committee of the Japanese Dermatological Association in February 2010. In this new unified version for all three biologic agents including ustekinumab, requirements for clinical facilities for the use of biologic agents, contents of safety measures against reactivation of tuberculosis and hepatitis B, and recommendable combination therapies with biologic agents, have been renewed and added. This guideline/safety manual has been prepared to assist dermatology specialists experienced in clinical practice of psoriasis to use biologic agents safely and properly.

著者

Hiroki KIKUCHI

出版者

グローバルビジネスリサーチセンター・東京大学MERC

雑誌

Annals of Business Administrative Science (ISSN:13474464)

巻号頁・発行日

pp.0160605a, (Released:2016-08-09)

参考文献数

17

被引用文献数

2 5

---

The Tokaido Shinkansen began operating in 1964 and ran at globally unprecedented speeds of more than 200 kmph. Comparison with the operating speed of aircraft necessitated further improvement of the operating speed of Shinkansen. Nevertheless, there was no improvement until 20 years. During that period, the maximum speed of test cars, the highest technically feasible speed, improved. Rather than technical factors, the following social and organizational factors impeded the improvement of the operating speed. (1) The social factor was the prioritization of environmental countermeasures to improvements in speed because of the noise pollution lawsuits and noise regulation. (2) The organizational factor was the need to secure the slack time due to frequent strikes and delays when Shinkansen was managed by Japan National Railways (JNR). However, around the time of the splitting and privatization of JNR in 1987, noise regulation was relaxed and lawsuits were settled. Furthermore, the labor movement settled down with the privatization of JNR; consequently, labor unions were dismantled. These events resolved preventive factors and led to the improvement of operating speeds.

著者

Haruta Mitsutaka Kurata Hiroki

出版者

Nature Publishing Group

雑誌

Scientific Reports (ISSN:20452322)

巻号頁・発行日

vol.2, 2012-02-07

被引用文献数

34

---

原子分解能で有機結晶薄膜中の欠陥構造観察に成功-有機デバイス材料の構造評価へ向けた新展開-. 京都大学プレスリリース. 2012-02-08.

著者

柳瀬 利彦 廣木 桂一 伊藤 昭博 柳井 孝介

出版者

一般社団法人 人工知能学会

雑誌

人工知能学会論文誌 (ISSN:13460714)

巻号頁・発行日

vol.26, no.5, pp.621-637, 2011 (Released:2011-07-20)

参考文献数

34

---

We propose a computing platform for parallel machine learning. Learning from large-scale data has become common, so that parallelization techniques are increasingly applied to machine learning algorithms in order to reduce calculation time. Problems of parallelization are implementation costs and calculation overheads. Firstly, we formulate MapReduce programming model specialized in parallel machine learning. It represents learning algorithms as iterations of following two phases: applying data to machine learning models and updating model parameters. This model is able to describe various kinds of machine learning algorithms, such as k-means clustering, EM algorithm, and linear SVM, with comparable implementation cost to the original MapReduce. Secondly, we propose a fast machine learning platform which reduces the processing overheads at iterative procedures of machine learning. Machine learning algorithms iteratively read the same training data in the data application phase. Our platform keeps the training data in local memories of each worker during iterative procedures, which leads to acceleration of data access. We evaluate performance of our platform on three experiments. Our platform executes k-means clustering 2.85 to 118 times faster than the MapReduce approach, and shows 9.51 times speedup with 40 processing cores against 8 cores. We also show the performance of Variational Bayes clustering and linear SVM implemented on our platform.

著者

井田 弘明 江口 勝美

出版者

日本臨床免疫学会

雑誌

日本臨床免疫学会会誌 (ISSN:09114300)

巻号頁・発行日

vol.30, no.2, pp.90-100, 2007 (Released:2007-04-30)

参考文献数

41

被引用文献数

2 4 2

---

TNF-associated periodic syndrome (TRAPS)は,TNFが病態の中心と考えられる遺伝性周期性発熱症候群の一つである.TNFRSF1A(TNFR1)分子が細胞表面に留まり,TNFからの反応が持続するため,発熱などの様々なTRAPS症状が出現すると単純に考えられてきた.ところが,最近,TNFRSF1A分子の切断異常がみられない症例や突然変異のないTRAPS症例もあること,さらに孤発例も存在することが判明し,TRAPSとは大変heterogeneousな症候群であることがわかってきた.最近,細胞表面に発現されないTNFRSF1A分子が,TNFと無関係に細胞内で凝集し,NF-κBの活性化やアポトーシス誘導を生じていることも報告され,TRAPSの病因は混沌としている.本邦において,現在までTNFRSF1A遺伝子に突然変異をもつTRAPS症例は5家系15名と少ないが,突然変異のない孤発例は多い.本稿では,TRAPSについて自験例を提示しながら臨床像を紹介するとともに,TNFRSF1A分子の発現制御機構から考えられるTRAPSの病因,その病因とこれまで経験した症例から検討した診断のためのフローチャート,および,現存の治療法と私たちが試みた新しい治療法などを解説した.

著者

馬場 健司 木村 宰 鈴木 達治郎

出版者

Sociotechnology Research Network

雑誌

社会技術研究論文集 (ISSN:13490184)

巻号頁・発行日

vol.2, pp.68-77, 2004

被引用文献数

4

---

近年急速に導入が拡大している風力発電の立地, 大規模ウィンドファームの開発については, いくつかの公益を巡ってコンフリクトが発生するケースがしばしばみられる. 立地プロセスにおけるアクターの参加の場や意思決定手続きについて, 文献調査とヒアリング調査により日米のケースを比較した結果, 以下が明らかとなった. 日本では自然公園での立地ケースについては公式プロセスの中で景観に限定したアジェンダが設定されるのみであるのに対して, 制度要求に基づく環境影響評価が適用された米国の洋上立地ケースでは, 第三者的専門家による非公式プロセスが補完しながら, そこで得たインプットが公式プロセスへとフィードバックされるなど, 事業の早い段階から幅広い参加の場とアジェンダが設定されている.

著者

Yu Fukuoka El-Sayed Khafagy Takahiro Goto Noriyasu Kamei Kozo Takayama Nicholas A. Peppas Mariko Takeda-Morishita

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.41, no.5, pp.811-814, 2018-05-01 (Released:2018-05-01)

参考文献数

14

被引用文献数

24

---

In previous studies we showed that the complexation hydrogels based in poly(methacrylic acid-g-ethylene glycol) [P(MAA-g-EG)] rapidly release insulin in the intestine owing to their pH-dependent complexation properties; they also exhibit a high insulin-loading efficiency, enzyme-inhibiting properties, and mucoadhesive characteristics. Cell-penetrating peptides (CPPs), such as oligoarginines [hexa-arginine (R6), comprising six arginine residues], have been employed as useful tools for the oral delivery of therapeutic macromolecules. The aim of our study was to investigate the combination strategy of using P(MAA-g-EG) hydrogels with R6-based CPPs to improve the intestinal absorption of insulin. A high efficiency of loading into crosslinked P(MAA-g-EG) hydrogels was observed for insulin (96.1±1.4%) and R6 (46.6±3.8%). In addition, immediate release of the loaded insulin and R6 from these hydrogels was observed at pH 7.4 (80% was released in approximately 30 min). Consequently, a strong hypoglycemic response was observed (approximately 18% reduction in blood glucose levels) accompanied by an improvement in insulin absorption after the co-administration of insulin-loaded particles (ILP) and R6-loaded particles (ALP) into closed rat ileal segments compared with that after ILP administration alone. These results indicate that the combination of P(MAA-g-EG) hydrogels with CPPs may be a promising strategy for the oral delivery of various insulin preparations as an alternative to conventional parenteral routes.

著者

Wei Huang

出版者

Global Business Research Center

雑誌

Annals of Business Administrative Science (ISSN:13474464)

巻号頁・発行日

pp.0180921a, (Released:2018-10-11)

参考文献数

11

被引用文献数

7

---

In existing research on new product development, it has been believed that the product development by companies needs to reflect the changes in customer needs. Particularly, for products in which continual development is a characteristic, customer needs must be addressed at multiple points in time. However, by comparing the cases of two companies from the online game industry, we found that long-term performance of a company which responded flexibly suffered a drop, with the ratio of new users dropping and the user attrition rate increasing. Therefore, we believed that too much attention was paid to the requests of lead users.

著者

Ron M. L. Ates

出版者

The Plankton Society of Japan, The Japanese Association of Benthology

雑誌

Plankton and Benthos Research (ISSN:18808247)

巻号頁・発行日

vol.12, no.1, pp.71-77, 2017-02-28 (Released:2017-02-28)

参考文献数

86

被引用文献数

1 24

---

Instances of predation and scavenging of jellyfish (pelagic Scyphozoa, Hydrozoa and Ctenophora) by benthic invertebrates are reviewed and presented. Sea anemones and decapod crabs are widespread as well as common predators or scavengers of jellyfish. Dead or dying jellyfish are also preyed upon by species of Echinodermata.

著者

永田 修一

出版者

公益社団法人 日本マリンエンジニアリング学会

雑誌

マリンエンジニアリング (ISSN:13461427)

巻号頁・発行日

vol.47, no.4, pp.585-590, 2012-07-01 (Released:2013-12-20)

参考文献数

35

被引用文献数

1

著者

Shuri Kato Asako Matsumoto Kensuke Yoshimura Toshio Katsuki Kojiro Iwamoto Yoshiaki Tsuda Shogo Ishio Kentaro Nakamura Kazuo Moriwaki Toshihiko Shiroishi Takashi Gojobori Hiroshi Yoshimaru

出版者

日本育種学会

雑誌

Breeding Science (ISSN:13447610)

巻号頁・発行日

vol.62, no.3, pp.248-255, 2012 (Released:2012-11-01)

参考文献数

36

被引用文献数

4 17

---

Numerous cultivars of Japanese flowering cherry (Prunus subgenus Cerasus) are recognized, but in many cases they are difficult to distinguish morphologically. Therefore, we evaluated the clonal status of 215 designated cultivars using 17 SSR markers. More than half the cultivars were morphologically distinct and had unique genotypes. However, 22 cultivars were found to consist of multiple clones, which probably originate from the chance seedlings, suggesting that their unique characteristics have not been maintained through propagation by grafting alone. We also identified 23 groups consisting of two or more cultivars with identical genotypes. Most members of these groups were putatively synonymously related and morphologically identical. However, some of them were probably derived from bud sport mutants and had distinct morphologies. SSR marker analysis provided useful insights into the clonal status of the examined Japanese flowering cherry cultivars and proved to be a useful tool for cultivar characterization.