著者

原田 槙葉 千田 真喜子

雑誌

2019年度 情報処理学会関西支部 支部大会 講演論文集 (ISSN:1884197X)

巻号頁・発行日

no.2019, 2019-09-13

著者

仙田 麻美 千田 眞喜子

雑誌

2019年度 情報処理学会関西支部 支部大会 講演論文集 (ISSN:1884197X)

巻号頁・発行日

no.2019, 2019-09-13

著者

長谷川 彩楽 千田 眞喜子

雑誌

2019年度 情報処理学会関西支部 支部大会 講演論文集 (ISSN:1884197X)

巻号頁・発行日

no.2019, 2019-09-13

著者

松本 精一

出版者

社団法人 農業農村工学会

雑誌

農業土木学会誌 (ISSN:03695123)

巻号頁・発行日

vol.70, no.10, pp.951-952, 2002-10-01 (Released:2011-08-11)

著者

濱 由樹子

出版者

津田塾大学

巻号頁・発行日

2009

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博士論文

著者

高田理夫

出版者

京都大学

雑誌

京都大学防災研究所年報

巻号頁・発行日

vol.28(A), 1985

著者

中島 正愛

出版者

日本建築学会

雑誌

建築雑誌 (ISSN:00038555)

巻号頁・発行日

no.1589, 2009-04-20

著者

上田 夏生 坪井 一人 宇山 徹

出版者

公益社団法人 日本ビタミン学会

雑誌

ビタミン (ISSN:0006386X)

巻号頁・発行日

vol.85, no.11, pp.604-607, 2011-11-25 (Released:2017-10-10)

参考文献数

34

被引用文献数

1

著者

大高 泉 遠藤 優介

出版者

一般社団法人 日本科学教育学会

雑誌

日本科学教育学会年会論文集 36 (ISSN:21863628)

巻号頁・発行日

pp.139-142, 2012-08-27 (Released:2018-05-16)

被引用文献数

1

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ドイツにおけるPISAショック後の教育政策と科学カリキュラム改革の展開について、KMKによる教育スタンダードの策定、科学の教育スタンダードの意味内容及び評価と各州への波及状況、新たなカリキュラムとしてのChemie im Kontextの開発動向等々の面から、その一端を明らかにした。

著者

山梨 義英

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.139, no.12, pp.1485-1494, 2019-12-01 (Released:2019-12-01)

参考文献数

38

被引用文献数

2

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Several fat-soluble compounds such as cholesterol and fat-soluble vitamins have important physiological activities in the body, and their excess and/or deficiency have been reported to be closely associated with the onset and progression of several conditions such as lifestyle-related diseases. It is important to clarify not only the physiological activities but also in vivo kinetics of fat-soluble compounds to understand their in vivo activity (toxicity). This review introduces our recent (reverse) translational research in a combination of basic and clinical studies to reveal the regulatory mechanisms of in vivo behaviors of fat-soluble compounds and effects of their disruption in humans.

著者

豊田 新 高原 周一 宮川 和也 守田 益宗 青木 一勝 佐藤 幸子 坂根 弦太 青木 宏之 蜂谷 和明 矢城 陽一朗 重松 利信 那須 浩郎 篠原 隆 宮宅 康郎 渡邉 誠 今井 剛樹 今山 武志 兵藤 博信 片山 敏和 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構理科教育センター 岡山理科大学教育支援機構学習支援センター 岡山理科大学教育支援機構学習支援センター 岡山理科大学理学部応用物理学科 岡山理科大学理学部応用物理学科 岡山理科大学自然科学研究所 岡山理科大学自然科学研究所 岡山理科大学非常勤講師

雑誌

岡山理科大学教育実践研究 = Okayama University of Science Educational Practice Research (ISSN:24339946)

巻号頁・発行日

no.1, 2017

著者

金沢 文緒 KANAZAWA Fumio

出版者

岩手大学教育学部

雑誌

岩手大学教育学部研究年報 = The Annual Report of the Faculty of Education Iwate University (ISSN:03677370)

巻号頁・発行日

vol.77, pp.17-39, 2018-03-28

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The wood carving, Virgin and Child on the Crescent, was acquired by the Department of Art and Design, Faculty of Education, Iwate University, around 1960. It was purchased as art-education material for students, and the relevant art-historical research has not been conducted in the 50 years since its acquisition. This study elucidates the background of the workʼs production, as well as the reception of such Christian art in modern Japan. This paper is the first report of the study.The first part of the paper describes the characteristics of the sculpture, based on visual observation. The second part presents the results of wood identification research, as preparation for art historical investigation. The third part reveals when and where the work was executed, based on iconographic analysis, and elucidates its function through consideration of the cultural environment. The fourth part explores the context of the purchase of the work by Iwate University.In sum, the limewood sculpture was produced in Southern Germany in the second half of the fifteenth century, and the iconography of “Virgin and Child on the Crescent” is closely related to the cult of the Virgin Mary, which was widespread in Germany before the Protestant Reformation. In Japan, the sculpture was originally located in Kobe, where many Germans have lived since the opening of the country.

著者

Hiroyuki Koyama Satoshi Yasuda Shota Kakoi Yasuhisa Ohata Yuki Shimizu Chie Hasegawa Akiko Hayakawa Tomoyuki Akiyama Takashi Yagi Daisuke Aotani Kenro Imaeda Keiichi Ozono Hiromi Kataoka Tomohiro Tanaka

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.3298-19, (Released:2019-11-29)

参考文献数

24

被引用文献数

8

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A 40-year-old Japanese woman presented to our hospital with general fatigue and muscle weakness. She had a history of premature loss of deciduous teeth at 4 years old, her serum alkaline phosphatase (ALP) activity was as low as 91 U/L, and radiologic studies revealed thoracic deformity and sacroiliac calcification. Genetic sequencing revealed a heterozygous c.1559delT mutation in the tissue non-specific alkaline phosphatase gene (ALPL). Based on these findings, she was diagnosed with hypophosphatasia (HPP), and treatment with asfotase alfa, a recombinant human tissue-nonspecific alkaline phosphatase (TNSALP), was initiated. After six months of treatment with asfotase alfa, improvements were observed in the SF-36 score, six-minute walk distance, and grasping power. Although the overdiagnosis needs to be avoided, HPP should be considered in patients with undiagnosed musculoskeletal symptoms and a low serum ALP activity.

著者

寺崎 昌男

出版者

大学教育学会

雑誌

大学教育学会誌 (ISSN:13442449)

巻号頁・発行日

vol.31, no.2, pp.3-12, 2009-11

著者

Ryoko Murayama Maiko Oya Mari Abe-Doi Makoto Oe Chieko Komiyama Hiromi Sanada

出版者

International Research and Cooperation Association for Bio & Socio-Sciences Advancement

雑誌

Drug Discoveries & Therapeutics (ISSN:18817831)

巻号頁・発行日

vol.13, no.5, pp.288-293, 2019-10-31 (Released:2019-11-14)

参考文献数

19

被引用文献数

5

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Paclitaxel, a taxane, is frequently administered intravenously as an anticancer agent. When a peripheral intravenous catheter is used for paclitaxel infusion, clinical nurses often observe signs such as slight swelling at the catheter placement site, lack of blood return, and difficulty in continuing the infusion. However, the cause(s) of such phenomena at the puncture site has not yet been elucidated. The aim of this study was to obtain ultrasonography images of subcutaneous tissues and veins of patients undergoing paclitaxel and carboplatin chemotherapy and compare ultrasonography images taken immediately before catheter removal with those of patients receiving other types of taxanes. We studied 24 patients receiving chemotherapy, including seven receiving paclitaxel and carboplatin chemotherapy, through a peripheral intravenous catheter in a chemotherapy unit for outpatients of a university hospital in Japan. Ultrasonography images of venipuncture sites were obtained before catheter insertion and immediately before catheter removal. We observed subcutaneous edema in the absence of visible manifestations at the puncture sites of all patients undergoing paclitaxel and carboplatin chemotherapy, but not in any patients receiving other types of taxanes. When vesicant agents and vehicles have caused subclinical subcutaneous edema, clinical nurses may detect early slight extravasation by using ultrasonography.

著者

萩原 建次郎 ハギワラ ケンジロウ Kenjiro Hagiwara

雑誌

立教大学教育学科研究年報

巻号頁・発行日

vol.53, pp.65-77, 2010-03-20

著者

Noriko Inoue Tomoko Ohkusa Tomoko Nitta Masahiko Harada Kazuya Murata Masunori Matsuzaki

出版者

The Japanese Circulation Society

雑誌

JAPANESE CIRCULATION JOURNAL (ISSN:00471828)

巻号頁・発行日

vol.65, no.11, pp.1001-1003, 2001 (Released:2001-10-25)

参考文献数

5

被引用文献数

1

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A 26-year-old man had a loss consciousness for a few minutes while smoking in the standing position, and was referred to hospital. No abnormalities were found in a computed tomography examination of his head, in a 24-h electrocardiogram or in an exercise tolerance test. The head-up tilt test (HUT) while tobacco smoking elicited a positive response in the tilted position, but the HUT without tobacco smoking was negative. The most noteworthy effect of tobacco smoking during the HUT was the high level of plasma epinephrine compared to the levels seen during supine smoking or the HUT alone. Syncope induced by tobacco smoking in the standing position is rare and the mechanism may be the same as that underlying neurally mediated syncope. (Jpn Circ J 2001; 65: 1001 - 1003)

著者

Neunghoe KIM Jongwook JEONG Mansoo HWANG

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Transactions on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E102.D, no.12, pp.2433-2434, 2019-12-01 (Released:2019-12-01)

参考文献数

3

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Free/libre open source software (FLOSS) are being rapidly employed in several companies and organizations, because it can be modified and used for free. Hence, the use of FLOSS could contribute to its originally intended benefits and to the competence of its users. In this study, we analyzed the effect of using FLOSS on related competences. We investigated the change in the competences through an empirical study before and after the use of FLOSS among project participants. Consequently, it was confirmed that the competences of the participants improved after utilizing FLOSS.

著者

Masaru Kunitomo Yu Yamaguchi Satomi Kagota Noriko Yoshikawa Kazuki Nakamura Kazumasa Shinozuka

出版者

The Japanese Pharmacological Society

雑誌

Journal of Pharmacological Sciences (ISSN:13478613)

巻号頁・発行日

vol.110, no.3, pp.354-361, 2009 (Released:2009-07-17)

参考文献数

50

被引用文献数

26 36

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Cigarette smoking is a major risk factor for cardiovascular disease. The induction of oxidative stress by smoking plays a key role in the progression of atherosclerosis. However, the underlying mechanisms are not fully understood. In the present study, we investigated whether long-term smoking can accelerate the progression of atherosclerosis and whether oxidative stress is implicated in its pathogenesis. Apolipoprotein E–deficient spontaneously hyperlipidemic mice, a model of atherosclerosis, were exposed to the gas-phase of smoke, from which tar and nicotine had been removed, for 15 min a day, 6 days a week, for 16 weeks. Exposure to cigarette smoke significantly increased the serum levels of oxidative stress markers such as thiobarbituric acid–reactive substances, oxidatively modified low-density lipoproteins, and 3-nitrotyrosine, but it did not affect serum cholesterol and triglyceride levels. Exposure to smoke also accelerated the accumulation of total cholesterol levels in the aorta that was accompanied by an increase in 3-nitrotyrosine levels of the atherosclerotic mice. These changes in the serum and aorta that progressed with exposure to smoke were prevented by vitamin E administration. Our data suggest that chronic cigarette smoking promotes and aggravates atherosclerosis and that the antioxidant vitamin E exerts an anti-atherogenic effect via reduction of oxidative stress.

著者

木村重夫

出版者

KRT

巻号頁・発行日

vol.50,