著者

齋藤 太郎 飯田 明彦 小林 孝憲 成松 花弥 堀野 一人

出版者

社団法人 日本口腔外科学会

雑誌

日本口腔外科学会雑誌 (ISSN:00215163)

巻号頁・発行日

vol.66, no.6, pp.282-287, 2020-06-20 (Released:2020-08-20)

参考文献数

24

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Low-grade central osteosarcoma, a rare subtype of osteosarcoma, is less aggressive than conventional osteosarcoma. We report ac case of low-grade central osteosarcoma of the mandible. A 52-year-old woman presented to our department for treatment of a swelling in the right side of the mandible. Computed tomography revealed ground glass radiopaque lesions associated with an expansive growth pattern in the mandibular bone. Because a suspicion of low-grade central osteosarcoma was diagnosed In the biopsy sample provided from the previous hospital, the lesion was surgically resected. Histopathologically, the tumor consisted of a dense proliferation of spindle cells with mild atypia. At the periphery of the lesion, the normal cortical bone was invaded by tumor nests. Low-grade central osteosarcoma was diagnosed in the surgical specimen. Tumor recurrence has not been observed for more than 6 years after surgery. Low-grade central osteosarcoma is hard to differentiate from osteogenic benign neoplasm or bone malformation. Therefore, when radiographic findings reveal an expansive ground glass appearance, a bone biopsy including the normal cortical bone and the central part of the lesion is essential.