著者
Yuta Taniguchi Masao Iwagami Nobuo Sakata Taeko Watanabe Kazuhiro Abe Nanako Tamiya
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20200057, (Released:2020-06-13)
参考文献数
22

Background: With increasing age globally, more people may become vulnerable to food choking. We investigated the nationwide epidemiology of food choking deaths in Japan.Methods: Using Japanese Vital Statistics death data between 2006 and 2016, we identified food choking deaths based on the 10th revision of the International Statistical Classification of Diseases code W79 (Inhalation and ingestion of food causing obstruction of respiratory tract) as a primary diagnosis. We assessed the demographics of people with food choking deaths; temporal trends of food choking deaths by the year (overall and by age group), the day of year; and prefecture variations.Results: Overall, 52,366 people experienced food choking deaths (median age, 82 years, 53% were male, and 57% occurred at home). The highest numbers occurred January 1-3, and were lowest in June. Despite a stable total number of cases at around 4,000 yearly, from 2006 to 2016 the incidence proportion declined from 16.2 to 12.1 per 100,000 population among people aged 75-84 years. Among people ≥85 years, the incidence proportion peaked at 53.5 in 2008 and decreased to 43.6 in 2016. The number of food choking deaths varied by prefecture.Conclusions: There are temporal and regional variations of food choking deaths in Japan, possibly due to the consumption of Japanese rice cake (mochi), particularly over the New Year’s holiday.
著者
藤本 由香里
出版者
社団法人 日本印刷学会
雑誌
日本印刷学会誌 (ISSN:09143319)
巻号頁・発行日
vol.52, no.6, pp.474-483, 2015 (Released:2016-01-15)
参考文献数
37

Before the Japanese manga went global, it was adapted for each country. Even in the pirated editions, we can find specific adaptations in them, resulting from the need for printing. For example, the print style in which 4 pages are set into 1 page in China, and different craftsman who draw cover art for manga in Thailand. However, the most important problem to be solved was how to adapt manga, which involved reading from right to left, into the style of being read from left to right in languages such as English. This essay tells you how the book style of reading from right to left has become popular even in Western countries.
著者
Hyun-Kyung Chang Mal-Soon Shin Hye-Young Yang Jin-Woo Lee Young-Sick Kim Myoung-Hwa Lee Jullia Kim Khae-Hawn Kim Chang-Ju Kim
出版者
The Pharmaceutical Society of Japan
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.29, no.8, pp.1597-1602, 2006 (Released:2006-08-01)
参考文献数
41
被引用文献数
83 86

Prostate cancer is one of the most common non-skin cancers in men. Amygdalin is one of the nitrilosides, natural cyanide-containing substances abundant in the seeds of plants of the prunasin family that have been used to treat cancers and relieve pain. In particular, D-amygdalin (D-mandelonitrile-β-D-gentiobioside) is known to exhibit selective killing effect on cancer cells. Apoptosis, programmed cell death, is an important mechanism in cancer treatment. In the present study, we prepared the aqueous extract of the amygdalin from Armeniacae semen and investigated whether this extract induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells. In the present results, DU145 and LNCaP cells treated with amygdalin exhibited several morphological characteristics of apoptosis. Treatment with amygdalin increased expression of Bax, a pro-apoptotic protein, decreased expression of Bcl-2, an anti-apoptotic protein, and increased caspase-3 enzyme activity in DU145 and LNCaP prostate cancer cells. Here, we have shown that amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax. The present study reveals that amygdalin may offer a valuable option for the treatment of prostate cancers.
著者
近藤 徹
出版者
一般社団法人 ダム工学会
雑誌
ダム工学 (ISSN:09173145)
巻号頁・発行日
vol.21, no.3, pp.154-166, 2011-09-15 (Released:2011-09-26)
著者
渡邊 浩
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.108, no.5, pp.962-963, 2019-05-10 (Released:2020-05-10)
参考文献数
7

166 152 0 0 OA 本草図譜 巻5-96

著者
岩崎常正<岩崎潅園>//著

飯沼慾斎(1783-1865)の『本草図説』と並び称せられる江戸時代末に作られた二大植物図譜のひとつで、江戸下谷生まれの幕臣岩崎灌園(1786-1842)の著作。野生種、園芸種、外国産の植物の巧みな彩色図で、余白に名称・生態などについて説明を付し、『本草綱目』の分類に従って排列している。巻5-10は文政13(1830)年江戸の須原屋茂兵衛、山城屋佐兵衛の刊行。以下巻11-96は筆彩の写本で制作、三十数部が予約配本され、弘化元(1844)年に配本が完了した。当館本は、巻5-8が版本に手彩色、巻11-96が筆彩写本。本多豊後守助賢が配本されたもので、後に本草学史の研究で著名な植物病理学者、理学博士白井光太郎(1863-1932)の手に渡っていたものである。当館では、他に田安家旧蔵本(請求記号 に-25)等を所蔵する。

267 139 39 6 OA 植民地統治論

著者
泉哲 著
出版者
有斐閣
巻号頁・発行日
1924
著者
柴田 芳昭 今濱 敏信 和気 敏治 関根 功 川瀬 哲也 城元 孝之 湯浅 真
出版者
Japan Society of Corrosion Engineering
雑誌
Zairyo-to-Kankyo (ISSN:09170480)
巻号頁・発行日
vol.41, no.8, pp.525-534, 1992-08-15 (Released:2009-11-25)
参考文献数
36

The effect of tannic acid on the corrosion of mild steel in boiler systems was investigated by physicochemical methods using an autoclave and a test boiler. Tannic acid was found to be a good oxygen scavenger at pH 11 as well as hydrazine and sodium sulphite. Tannic acid inhibited corrosion of steel (i) at room temperature and atmospheric pressure and (ii) at high temperature and pressure. The maximum inhibition efficiency was about 97%. The inhibiting behavior of tannic acid at pH 7 was different from that at pH 11. At pH 7, tannic acid acted as an adsorption-type inhibitor and suppressed catholic reaction of corrosion of steel. At pH 11, tannic acid inhibited corrosion of steel not only as an effective oxygen scavenger but also an effective Schikorr reaction promoter (formation of Fe3O4). Tannic acid is believed to be an effective inhibitor in boiler systems.
著者
増田 俊夫 早見 崇 中條 大志 Hayami Takashi 中條 大志 Nakajo Hiroshi 原 道寛 Hara Michihiro 佐藤 潤一 Sato Junichi 寺本 好邦 Teramoto Yoshikuni 西尾 嘉之 Nishio Yoshiyuki
出版者
福井工業大学
雑誌
福井工業大学研究紀要 Memoirs of Fukui University of Technology (ISSN:18844456)
巻号頁・発行日
no.43, pp.284-292, 2013

Ethy1cellulose (EC) exhibits interesting behavior in the formation of liquid crystals. Early observations indicated that most cellulosics formed right-handed cholesteric structure. However, EC in chloroform and acetic acid (AA) solutions took left-handed cholesteric liquid crystals, whereas EC in dichloroacetic acid (DCA) solution had right-handed ones. In the present study, (phenylacetyl)ethylcellulose (PA-EC) was prepared by the reaction of phenylacetyl chloride with EC having a degree of ethyl substitution (DSEt) of 2.26 in N,N-dimethylacetamide solution using triethylamine as proton scavenger. Reactions were usually carried out at room temperature for one week, which provided a variety of phenylacetyl contents (degree of substitution of phenylacetyl (DSPa) = 0.02, 0.11, 0.32, and 0.43). The chloroform and AA solutions of PA-EC with DSPa = 0.32 displayed a right-handed cholesteric liquid crystalline phase, while the DCA solution showed a left-handed one.
著者
柳田 紀之 飯倉 克人 小倉 聖剛 王 怜人 浅海 智之 佐藤 さくら 海老澤 元宏
出版者
一般社団法人 日本アレルギー学会
雑誌
アレルギー (ISSN:00214884)
巻号頁・発行日
vol.64, no.10, pp.1341-1347, 2015 (Released:2015-12-29)
参考文献数
13

【目的】アドレナリン自己注射薬を誤射した3症例の臨床経過を検討し,報告する.  【症例1】50代女性がエピペン®0.3mgをトレーナーと間違えて自分の右大腿部に誤射した.収縮期/拡張期血圧は7分後に144/78mmHgと一過性の上昇を認め,14分後には軽快した.7分後に動悸を訴えた以外,自覚症状は注射部位の局所の痛みのみであった.  【症例2】6歳男児がエピペン®を用いて遊び,右第二指に誤射し,貫通した.貫通部位の発赤,腫脹を認めたが,保温のみで誤射80分後には軽減したため,帰宅した.【症例3】4歳女児がエピペン®を用いて遊び,右大腿に誤射した.誤射23分後に収縮期/拡張期血圧は123/70mmHgと一過性の上昇を認めたが軽快し,1時間後,帰宅した.  【考察・結語】アドレナリン自己注射薬の誤射による副反応は一過性であり,3例とも重篤な副反応は認めなかった.アドレナリン自己注射薬の誤射防止のため取り扱いには十分な注意が必要である.
著者
野村 駿
出版者
日本教育社会学会
雑誌
教育社会学研究 (ISSN:03873145)
巻号頁・発行日
vol.103, pp.25-45, 2018-11-30 (Released:2020-06-26)
参考文献数
21

本稿の目的は,「音楽で成功する」といった夢を掲げ,その実現に向けて活動するロック系バンドのミュージシャン(以下,バンドマン)を事例に,夢の実現可能性に関する解釈実践の内実を検討し,若者が夢を追い続ける社会的背景を明らかにすることである。バンドマンを対象とした質的調査の結果に基づき,次の4点を明らかにした。 第1に,夢の実現可能性に関するバンドマンの語りの特徴として,可能性と限界という2つの認識が内包されていることを示した。そして,なぜ夢の実現可能性に限界を感じながら,夢を追い続けることができるのかを検討した。 その結果,第2に,「夢の実現には時間がかかる」という認識枠組みが獲得されることによって,また第3に,周囲のバンド仲間の状況を選択的に参照する行為によって,夢を実現できていない自己の正当化と将来における夢の実現期待が同時に達成されることで,夢を追い続けることが可能になっていると指摘した。加えて,第4に,夢の実現可能性を低く見積もる因習的見解からの作用が,バンドマンの夢追いアスピレーションを加熱させることで,夢追いの継続という意図せざる帰結を導いてしまうことを明らかにした。 以上の知見をもとに,先行研究で論じられてきた進路選択・進路指導の実践を再考し,教育社会学においても積極的に学校外部へと視野を広げて,子ども・若者の進路選択プロセスを検討する必要があると論じた。
著者
Tatsuya Kasuyama Masaaki Sakamoto Rie Nakazawa
出版者
The Society of Physical Therapy Science
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.21, no.2, pp.195-199, 2009 (Released:2009-07-18)
参考文献数
16
被引用文献数
13 13

[Purpose] The purpose of this study was to clarify the intrinsic factors influencing the deep squatting posture and to investigate the utility of ankle joint dorsiflexion measurement using this posture. [Subjects] The study subjects were 71 healthy male individuals. [Methods] The subjects were asked to squatted with their heels down and then were divided into 2 groups: possible squatting and impossible squatting. The anthropometric characteristics of the subjects were assessed, and the flexibility and movement range of the lower extremities were tested. To identify the intrinsic factors influencing the deep squatting posture, a dediscriminant analysis was performed by a stepwise procedure. The sensitivity, specificity, and cutoff values for the factors were evaluated by receiver operating characteristic curve analysis. [Results] Of the 71 participants, 55 were assigned to the possible squatting group and the remaining to the impossible squatting group. Analysis revealed that body weight and ankle dorsiflexion flexibility were significantly associated with ability to assume the deep squatting posture. In particular, ankle dorsiflexion flexibility was strongly associated with the ability to assume this posture. [Conclusion] The impossible squatting group showed reduced ankle dorsiflexion. Thus, the deep squatting posture is useful for easy and objective method for measuring ankle joint dorsiflexion flexibility.
著者
Nuraly S. Akimbekov Ilya Digel Dinara K. Sherelkhan Afzalunnessa B. Lutfor Mohammed S. Razzaque
出版者
JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY
雑誌
ACTA HISTOCHEMICA ET CYTOCHEMICA (ISSN:00445991)
巻号頁・発行日
vol.53, no.3, pp.33-42, 2020-06-26 (Released:2020-06-26)
参考文献数
100

There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords “vitamin D,” “intestines,” “gut microflora,” “bowel inflammation”. Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression.