著者

Noriki Kutsumura Masatoshi Iijima Shohei Toguchi Takao Saito

出版者

The Chemical Society of Japan

雑誌

Chemistry Letters (ISSN:03667022)

巻号頁・発行日

vol.40, no.11, pp.1231-1232, 2011-11-05 (Released:2011-10-08)

参考文献数

21

被引用文献数

8

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We have investigated the DBU-promoted HBr-elimination of vicinal dibromides having an adjacent O- and/or N-functional group under mild basic conditions. The elimination of 1-oxygen-functionalized 2,3-dibromopropanes was more regioselective than that of 1-nitrogen-functionalized 2,3-dibromopropanes. This observation suggests that the elimination selectivity is affected by the electronegativity of the neighboring heteroatoms themselves and not by the entire functional group.