著者

HIGO KEN-ICHI YAMAMOTO OSAMU

出版者

日本放射線影響学会

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.26, no.3, pp.353-359, 1985-09

被引用文献数

2

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In the presence of tritiated water (HTO), Escherichia coil NG30 was grown in sealed test tubes containing synthetic medium (M9-0.4% glucose-0.005% arginine), and cell growth was monitored by measuring medium turbidity. Catalase (60 μg/ml) was added to the medium to reduce HTO associated accumulation of H_2O_2. A positive correlation between increasing concentration of HTO in the medium and the growth suppression was seen. A similar trend was observed when cells were grown under continuous irradiation of ^<60>Co gamma-rays. The RBE of HTO beta-rays relative to gamma-rays was calculated from the accumulated doses to the cultures. It was found to be 1.7 when the growth was inhibited to 60% of the control, and increased with decreasing dose.