著者

小林 富美惠 井上 信一

出版者

日本原生生物学会

雑誌

原生動物学雑誌 (ISSN:03883752)

巻号頁・発行日

pp.JJP17-01, (Released:2017-12-01)

参考文献数

62

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Malaria remains one of the most serious infectious diseases with the high morbidity and mortality among children in the world. Malaria is caused by protozoan parasites of genus Plasmodium.An efficient vaccine for malaria has not successfully developed for the eradication yet. Thus, to support malaria vaccine development, we have to uncover the mechanisms for protective immunity against Plasmodium infection. We have clarified γδ T cell-related protective immunity against erythrocytic stages of malaria parasites by using low virulent Plasmodium berghei-infected mice. Here we summarize recent advances, including our studies, in understanding mechanisms of immune response to erythrocytic stages of Plasmodium infection.