著者

萩原 弥四郎 戸井 道夫 伯野 中彦 石原 真 伊藤 賢章 浦野 俊雄

出版者

千葉大学

雑誌

千葉医学会雑誌 (ISSN:00093459)

巻号頁・発行日

vol.41, no.4, pp.384-397, 1965-11-28

---

Surface circulation of the body in cats and human materials was measured by a thermoelectric element. The element type is unique in that it uses a thermopile instead of a double thermocouple. The skin blood flow at the capillary level was measured with this element, uninterfered with the muscle blood flow and arteriovenous shunt in the precapillary region. 1) The blood flow of skin, in the resting stage, shows a slight undulation which is mostly independent of systemic blood pressure change. However, in some cases, the skin blood flow decreases when systemic blood pressure markedly falls. 2) The skin blood flow decreases after local intra-arterial injection or intravenous administration of epinephrine and norepinephrine. The blood flow decreasing action of epinephrine is diminished with pretreatment of phentolamine (regitine) and enhanced with dichloroisoproterenol (DCI). The action of norepinephrine is blocked with phentolamine but not influenced by DCI. 3) Constriction of blood vessels in the skin is probably due to adrenergic (α-type) control, while dilatation seemed only slightly adrenergic (β-type) and parasympathetic influenced, some secondary effects such as metabolic factors being possibly concerned. 4) In some experiments on the- human being, mental work immediately decreases the skin blood flow in many cases. 5) The following points were discussed in the present paper : merits and demerits of this method, factors which influence the blood flow change, method of setting the element on the skin, standard to calculate the blood flow value, influence of clamping the inflow vessel, mechanism of constriction and dilation of skin blood vessel, psychic influence on the skin blood flow and application of this method in clinical use.