著者

室橋 豊穂 関 叉蔵 吉田 幸之助

出版者

JAPANESE SOCIETY FOR TUBERCULOSIS

雑誌

結核 (ISSN:00229776)

巻号頁・発行日

vol.29, no.7, pp.248-252, 1954-07-15 (Released:2011-05-24)

参考文献数

6

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Comparative studies were made on the cultural and immunobiological characteristics between Scandinavian and Japanese BCG strains.Each of them grew very nice on the potato-media and their growths were good on the bilepotato medium even from the first transplantation. Their growths were also good on the Sauton medium, but the pellicles were rather thick compared with that of Japanese strain. The growth speed on this medium was slightly more rapid in Swedish and Norwegian strains than that of Danish and Japanese. but the viable units per mg of pellicle were the greatest in Japanese, strain.The bacillary size was compared on the smears prepared from Sauton-potato cultures and it was found that the three strains, Danish, Swedish and Japanese had almost the same average size with similar distribution curves, whereas, Norwegian strain only had rather big size like French strain reported in the foregoing paper.Virulence test as well as challenge test on guinea pigs did not show any difference among those four strains except the difference due to the different amount of viable units inoculated.From these results it is considered that for the maintenance of the original characteristics of BCG strain, it is best at present to maintain it only by the successive transplantation on bilepotato medium.