著者

夏井 美幸 川越 政美 永井 繁春 喬 志偉 佐藤 喜暁 フローレス マリア ジョリナルー 小泉 幸央 小代田 宗一 杉山 俊博

出版者

秋田医学会

雑誌

秋田医学 (ISSN:03866106)

巻号頁・発行日

vol.40, no.1, pp.1-12, 2013

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The glechoma hederacea subsp. grandis( G. grandis) is used as an herbal medicine and is supposed that the extract at the time of the bloom shade-drying is effective against a child's convulsion. Moreover, it may be considered as reduction of blood sugar level. In this study, the clinical test of the hair growth facilitatory effect of the G. grandis extract in human during one to three years showed remarkable improvement or a little improvement by evaluation at 95%(41 persons among 43 persons). With the mice, the tendency for hair growth was promoted compared with a control( physiological saline). Furthermore, we used the hair follicle organ culture system for the hair growth promoting substance from G. grandis extract. As a result, G. grandis in the growth phase after the bloom had remarkable growth effect, and found out having the remarkable hair growth effect in a fraction of aqueous phase from the extract especially. This aims at the establishment of the hair regenerative technology which utilizes the natural plant, G. grandis. It is possible to apply to the baldness and the alopecia caused by various factors, and preventive effect for the depilation, trichogenous, and the hair restoration action improve synergistic and it is effective as the external application medicine for the head with high safety compared with the scalp.