著者

永根 基雄

出版者

Kinki Brain Tumor Pathology Conference

雑誌

Neuro-Oncologyの進歩 (ISSN:18800742)

巻号頁・発行日

vol.22, no.3, pp.8-20, 2015-12-26 (Released:2015-12-26)

参考文献数

51

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Gliomas represent the most frequent malignant neoplasms that arise in the central nervous system. Astrocytic tumors comprise 78% of all gliomas and their histological grade (I – IV) is defined according to the current WHO classification. Although the prognosis of grade IV glioblastoma (GBM), the most malignant form of gliomas, is still detrimental, there have been progress in the management of these tumors since a number of confirming phase III clinical trials have been conducted in the last decade to provide with standard of care(SOC) therapies. Here I will focus on such pivotal trials for astrocytic tumors and discuss issues that need to be solved in the future studies.