文献一覧: 田川博昭 (著者)

1 0 0 0 OA Antitumor Agents. V. Synthesis and Antileukemic Activity of E-Ring-Modified (RS)-Camptothecin Analogues

著者: 江島明男寺沢弘文杉森正道大薄悟松本建介川戸康義安岡周美田川博昭
出版者: The Pharmaceutical Society of Japan
雑誌: Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日: vol.40, no.3, pp.683-688, 1992-03-25 (Released:2008-03-31)
参考文献数: 15
被引用文献数: 13 21

Several E-ring-modified analogues of (RS)-camptothecin were synthesized by total synthesis via Friedlander condensation and evaluated for cytotoxicity and antitumor activity against P388 mouse leukemia cells. Among them, (RS)-20-deoxyamino-7-ethyl-10-methoxycamptothecin (25c) was found to be more active than (RS)-camptothecin (1) in the in vivo assay.

2018-03-12 11:50:59
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1 0 0 0 Antitumor Agents. V. Synthesis and Antileukemic Activity of E-Ring-Modified (RS)-Camptothecin Analogues.

著者: 江島明男寺沢弘文杉森正道大薄悟松本建介川戸康義安岡周美田川博昭
出版者: 公益社団法人日本薬学会
雑誌: CHEMICAL & PHARMACEUTICAL BULLETIN (ISSN:00092363)
巻号頁・発行日: vol.40, no.3, pp.683-688, 1992
被引用文献数: 21

2017-01-12 06:34:12
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