- West-Japanese Society of Orthopedics & Traumatology
- 整形外科と災害外科 (ISSN:00371033)
- vol.32, no.3, pp.755-758, 1984 (Released:2010-03-16)
In crystallographic study of tophaceous substances and deposits in gouty synovial fluids using differential-interference microscopy, polarized light microscopy and X-ray diffraction method, the following results were obtained.1) Substances of subcutaneous tophi and deposits in gouty synovial fluids were found to be needle-like crystals. By polarized-light microscopy, they were negatively birefringent with extinction on the long axis.2) The needle-like crystals obtained from subcutaneous tophi and/or synovial fluids in gouty patients have been positively confirmed as monosodium urate monohydrate (NaC5H3N4O3·H2O) by X-ray diffraction technics.