著者
JAMES V. NEEL WILLIAM J. SCHULL AKIO A. AWA CHIYOKO SATOH HIROO KATO MASANORI OTAKE YASUHIKO YOSHIMOTO
出版者
Journal of Radiation Research Editorial Committee
雑誌
Journal of Radiation Research (ISSN:04493060)
巻号頁・発行日
vol.32, no.SUPPLEMENT, pp.347-374, 1991 (Released:2006-05-31)
参考文献数
75
被引用文献数
5

The data collected in Hiroshima and Nagasaki during the past 40 years on the children of survivors of the atomic bombings and on the children of a suitable control population are analyzed on the basis of the newly revised estimates of radiation doses. No statistically significant effects emerge with respect to eight different indicators. Since, however, it may confidently be assumed some mutations were induced, we have taken the data at face value and calculated the minimal gametic doubling doses of acute radiation for the individual indicators at various probability levels. An effort has also been made to calculate the most probable doubling dose for the indicators combined. The latter value is between 1.7 and 2.2 Sv. It is suggested the appropriate figure for chronic radiation would be between 3.4 and 4.5 Sv. These estimates suggest humans are less sensitive to the genetic effects of radiation than has been assumed on the basis of past extrapolations from experiments with mice.