著者

Chih-Yang Chiu Chia-Ying Li Chao-Chen Chiu Masatake Niwa Susumu Kitanaka Amooru Gangaiah Damu E-Jian Lee Tian-Shung Wu

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.53, no.9, pp.1118-1121, 2005 (Released:2005-09-01)

参考文献数

31

被引用文献数

11 20

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Three new flavonoid derivatives, 6′′′-O-acetyl amurensin (1), 6′′′-O-acetyl phellamurin (3) and (2R)-phellodensin-F (5), together with thirty known compounds have been isolated from the leaves of Phellodendron japonicum MAXIM. Their structures were established by means of spectroscopic analysis, including extensive 2D NMR and Mass spectra. The known compounds were identified by comparison with published physical and spectral data. The isolated compounds were screened for their in vitro antioxidant activity through DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. Compounds quercetin and phellodenin-A demonstrated significant radical scavenging activity.