著者
Mariko Kobayashi Shinji Endo Yukako Hamano Mamiko Imanishi Daisuke Akutsu Akinori Sugaya Daisuke Ochi Toshikazu Moriwaki Ichinosuke Hyodo
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.55, no.2, pp.127-130, 2016 (Released:2016-01-15)
参考文献数
16
被引用文献数
1 6

Combination chemotherapy of mFOLFOX6 (5-fluorouracil, leucovorin, and oxaliplatin) plus panitumumab, a fully human monoclonal antibody against epidermal growth factor receptor (EGFR), is one of the standard treatments for metastatic colorectal cancer (mCRC) without KRAS mutation. A few reports suggested no need of dose adjustment of cetuximab, a similar chimeric anti-EGFR antibody, in patients with renal impairment. However, panitumumab combined with cytotoxic drugs for hemodialysis patients has not been reported. We herein report a case of a hemodialysis mCRC patient successfully treated with mFOLFOX6 and panitumumab combination therapy.