著者
Stefano TETÈ Vincenzo Luca ZIZZARI Bruna BORELLI Marianna DE COLLI Susi ZARA Roberto SORRENTINO Antonio SCARANO Enrico GHERLONE Amelia CATALDI Fernando ZARONE
出版者
日本歯科理工学会
雑誌
Dental Materials Journal (ISSN:02874547)
巻号頁・発行日
vol.33, no.1, pp.7-15, 2014-01-30 (Released:2014-02-01)
参考文献数
34
被引用文献数
5 31

Human gingival fibroblasts (HGFs) were cultured onto CAD/CAM zirconia (Group A), CAD/CAM zirconia after polishing (Group B), CAD/CAM lithium disilicate after polishing (Group C), and feldspathic ceramic (Group D) to evaluate their proliferation and adhesion potential. After 3 h, HGF adhesion was similar in all groups. Later, HGFs closely adhered to surfaces, particularly onto groups B, C and D, acquiring an elongated shape. Proliferation assay showed no differences in cell viability among the groups after 24 h, while significant increase was shown after 72 h in Groups B and C. After 24 h, similar Collagen I levels were found in all groups, while after 72 h Groups B and C revealed a deep reduction in respect to the 24 h level. In vitro, HGF behavior may reflect variability in soft tissue response to different surface materials for prosthetic restorations, and support that polished zirconia is able to achieve a better integration in vivo in respect to the other materials.