著者

Yurie Hirata Shinji Kamei Fuminori Tatsumi Masashi Shimoda Akihito Tanabe Junpei Sanada Yoshiro Fushimi Shintaro Irie Tomoatsu Mune Kohei Kaku Hideaki Kaneto

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.56, no.12, pp.1527-1529, 2017-06-15 (Released:2017-06-15)

参考文献数

11

被引用文献数

1

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Succinic acid cibenzoline (CZ) is an antiarrhythmic agent often used for the treatment of tachyarrhythmia. However, hypoglycemia should be avoided in the treatment of diabetes. We herein report two late-stage elderly subjects who experienced a severe and prolonged hypoglycemic coma after the usage of CZ. These cases suggest that, when CZ is administered to elderly subjects with renal dysfunction and/or frailty, we should be aware of the possibility that this medicine may induce hypoglycemia and should adjust the dose as appropriate and monitor the concentration of CZ to avoid severe hypoglycemia.