著者
TETÈ Stefano ZIZZARI Vincenzo Luca BORELLI Bruna DE COLLI Marianna ZARA Susi SORRENTINO Roberto SCARANO Antonio GHERLONE Enrico CATALDI Amelia ZARONE Fernando
出版者
The Japanese Society for Dental Materials and Devices
雑誌
Dental Materials Journal (ISSN:02874547)
巻号頁・発行日
vol.33, no.1, pp.7-15, 2014
被引用文献数
31

Human gingival fibroblasts (HGFs) were cultured onto CAD/CAM zirconia (Group A), CAD/CAM zirconia after polishing (Group B), CAD/CAM lithium disilicate after polishing (Group C), and feldspathic ceramic (Group D) to evaluate their proliferation and adhesion potential. After 3 h, HGF adhesion was similar in all groups. Later, HGFs closely adhered to surfaces, particularly onto groups B, C and D, acquiring an elongated shape. Proliferation assay showed no differences in cell viability among the groups after 24 h, while significant increase was shown after 72 h in Groups B and C. After 24 h, similar Collagen I levels were found in all groups, while after 72 h Groups B and C revealed a deep reduction in respect to the 24 h level. <i>In vitro</i>, HGF behavior may reflect variability in soft tissue response to different surface materials for prosthetic restorations, and support that polished zirconia is able to achieve a better integration <i>in vivo</i> in respect to the other materials.