著者
Shozo TAKAYAMA Yoko NAKATSURU Mitsunobu MASUDA Hiroko OHGAKI Shigeaki SATO Takashi SUGIMURA
出版者
The Japanese Cancer Association
雑誌
GANN Japanese Journal of Cancer Research (ISSN:0016450X)
巻号頁・発行日
vol.75, no.6, pp.467-470, 1984 (Released:2008-03-17)
参考文献数
22

The mutagenic compound 2-amino-3-methylimidazo[4, 5-f]quinoline, originally isolated from broiled sardines and also present in cooked beef and beef extract, is being tested for carcinogenicity in F344 rats of both sexes. High incidences of tumors of the Zymbal gland, colon, small intestine and liver in males have been observed in the first 300 days of the experiment.