- 著者
- Tomone AMATSUBO Daijiro YANAGISAWA Shigehiro MORIKAWA Hiroyasu TAGUCHI Ikuo TOOYAMA
- 出版者
- 日本磁気共鳴医学会
- 雑誌
- Magnetic Resonance in Medical Sciences (ISSN:13473182)
- 巻号頁・発行日
- vol.9, no.3, pp.95-99, 2010 (Released:2010-09-27)
- 参考文献数
- 23
- 被引用文献数
- 9 21
The formation of senile plaques followed by deposition of amyloid β peptides (Aβ) are the earliest pathological changes of Alzheimer's disease (AD); thus, detection of the plaques remains the most important early diagnostic indicator of AD. Amyloid imaging is a noninvasive technique for visualizing senile plaques in the brains of patients with Alzheimer's using positron emission tomography (PET) or magnetic resonance (MR) imaging. Several types of probes have been developed for PET, but few ligands have been developed specifically for MR imaging detection of amyloid plaques. This review presents recent advances in amyloid imaging using MR imaging and includes our studies.