- 著者
- MASAYUKI ISHIHARA KAORU MURAKAMI KOICHI FUKUDA SHINGO NAKAMURA MASAHIRO KUWABARA HIDEMI HATTORI MASANORI FUJITA TOMOHARU KIYOSAWA HIDETAKA YOKOE
- 出版者
- The Society for Antibacterial and Antifungal Agents, Japan
- 雑誌
- Biocontrol Science (ISSN:13424815)
- 巻号頁・発行日
- vol.22, no.4, pp.223-227, 2017 (Released:2017-12-26)
- 参考文献数
- 20
- 被引用文献数
- 45 50
Hypochlorous acid (HOCl) solution (200 ppm, pH 6) was prepared and evaluated for their stabilities and microbicidal activities. We demonstrated that HOCl is unstable against ultraviolet (UV) light, sunshine, contact with air, and elevated temperature (≧25℃). Furthermore, in the HOCl solution, the presence of excess NH2- or CHO-containing organic compounds such as proteins and carbohydrates, or of inorganic ions such as NO2-, SO3-, PO3-, Fe2+, Cu2+, and CuS, resulted in the rapid consumption of HOCl by oxidation reactions, and significantly decreased the microbicidal activity of the HOCl solution against coliform bacteria and total viable cell count. Thus, production of stable HOCl solution requires formulation in pure water harboring concentrations as low as possible of various compounds and ions, as well as storage in dark and cool conditions (<10℃) to maintain the concentration of HOCl molecules and microbicidal activity.
- 著者
- YOKO SATO MASAYUKI ISHIHARA SHINGO NAKAMURA KOICHI FUKUDA MASAHIRO KUWABARA TOMOHIRO TAKAYAMA SUMIYO HIRUMA KAORU MURAKAMI MASANORI FUJITA HIDETAKA YOKOE
- 出版者
- The Society for Antibacterial and Antifungal Agents, Japan
- 雑誌
- Biocontrol Science (ISSN:13424815)
- 巻号頁・発行日
- vol.24, no.2, pp.103-108, 2019 (Released:2019-06-17)
- 参考文献数
- 19
- 被引用文献数
- 16 18
The bactericidal activity of heated bio-shell calcium oxide (BiSCaO) powder suspension (pH 12.4) , hypochlorous acid (HClO; pH 6), sodium hypochlorite (NaClO; pH 8) , povidone-iodine (Isodine solution®) , and chlorhexidine gluconate (Hibiscrub®) under organic matter contaminated environments were compared for tests conducted on wood scraps and pig skin pieces that were incubated with normal bacterial flora (total viable counts and coliform bacteria) . The test results showed that BiSCaO suspension had higher bactericidal activity than HClO and NaClO. Furthermore, more than 10-fold higher concentrations of antiseptics such as povidone-iodine and chlorhexidine gluconate were required to achieve bactericidal activity comparable to that of BiSCaO suspension. Our results demonstrate the possibility of using BiSCaO suspension under organic matter contaminated environments as a disinfectant for environmental and food hygiene applications.