- 著者
-
Yuya Aotsuka
Akiyuki Uzawa
Kazutaka Nishimura
Kazuho Kojima
Mika Yamaguchi
Takahiro Makino
Kazuo Nakamichi
Masayuki Saijo
Satoshi Kuwabara
- 出版者
- 一般社団法人 日本内科学会
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.55, no.12, pp.1645-1647, 2016-06-15 (Released:2016-06-15)
- 参考文献数
- 13
- 被引用文献数
-
11
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease that favors the cerebrum and typically occurs in immunosuppressed patients. We herein report the case of a 66-year-old man with PML, idiopathic CD4+ T lymphocytopenia (ICL), and chronic renal failure. Cranial magnetic resonance imaging (MRI) showed a crescent-shaped lesion in the left cerebellum, brainstem, and middle cerebellar peduncle. Although the patient did not present with HIV infection, collagen diseases, or tumors, JC virus DNA was detected in the cerebrospinal fluid. Clinicians should consider PML and ICL in the differential diagnosis if the patient develops progressive ataxia and a crescent-shaped cerebellar lesion on MRI.