- 著者
- Yoshimune Nonomura Mitsuki Omori Kei Kikuchi
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- pp.ess22333, (Released:2023-01-11)
- 被引用文献数
- 1
The friction characteristics of foaming body cleansers determine skin physical irritation, as well as the usability of the products. In this study, the friction of foam formed by a commercial body cleanser was evaluated using a sinusoidal-motion friction evaluation system. The friction profile of the foam was a hydrodynamic stable pattern, where the friction force increased with increasing velocity. In addition, soapbased cleansers, containing polyols, showed large friction coefficients. These properties suggest that the mechanical properties of the interfacial film and viscosity of the cleanser bulk affect friction properties. These findings assist in controlling the texture of body cleansers.
- 著者
- Kei Kikuchi Akiko Miki Hiroki Satoh Noriko Iba Rika Sato-Sakuma Hirokuni Beppu Yasufumi Sawada
- 出版者
- International Research and Cooperation Association for Bio & Socio-Sciences Advancement
- 雑誌
- Drug Discoveries & Therapeutics (ISSN:18817831)
- 巻号頁・発行日
- vol.13, no.4, pp.183-188, 2019-08-31 (Released:2019-09-18)
- 参考文献数
- 13
Patient narratives of adverse drug events (ADEs) often differ from the symptoms listed on the package inserts of pharmaceutical products using common ADE terminology and could be a source of great comfort to patients with the same disease. To explore this idea, we analyzed written narratives obtained from 48 patients with breast cancer using the NPO Corporation Database of Individual Patients' Experiences, Japan (DIPEx-Japan). Our analysis aimed to determine the utility of an "Adverse Drug Event Database" for use in clinical settings as a novel source of disease information in patients' own words. An analysis of transcripts from 29 patients, in which they recounted their treatment drugs and the time of onset and duration of ADEs in great detail, revealed several discrepancies between the language they used to describe various side effects and the standard ADE terminology on package inserts. We conclude that the language used to describe ADEs on package inserts is insufficient for helping patients as they struggle to recognize, internalize, and overcome ADEs, and argue the need for available, detailed information in the words of real patients about the nature of the ADEs predicted, as well as their clinical course and duration. Such information would be invaluable in supplementing the standardized language used on package inserts. Databases of patients' narrative accounts of ADEs are needed as information sources that can be reliably disseminated among patients.