著者
Enrico Tedeschi Sirio Cocozza Pasquale Borrelli Lorenzo Ugga Vincenzo Brescia Morra Giuseppe Palma
出版者
日本磁気共鳴医学会
雑誌
Magnetic Resonance in Medical Sciences (ISSN:13473182)
巻号頁・発行日
pp.cr.2016-0137, (Released:2017-03-27)
参考文献数
24
被引用文献数
9

We report the assessment of Dentate Nuclei (DN) R1 (1/T1) and R2* (1/R2*) values in a patient with relapsing-remitting Multiple Sclerosis, exposed to 22 standard (0.1 mmol/kg) doses of gadobutrol, who underwent eight relaxometric magnetic resonance (MR) measurements within two years. DN R1 did not significantly increase nor correlated with cumulative gadobutrol administration, even after a total dose of 130 ml. Likewise, DN R2* relaxometry remained unchanged. In conclusion, massive gadobutrol exposure did not induce significant DN relaxometry changes.