著者
MASASHI UEMA KENZO YONEMITSU YOSHIKA MOMOSE YOSHIKAZU ISHII KAZUHIRO TATEDA TAKAO INOUE HIROSHI ASAKURA
出版者
The Society for Antibacterial and Antifungal Agents, Japan
雑誌
Biocontrol Science (ISSN:13424815)
巻号頁・発行日
vol.26, no.2, pp.119-125, 2021 (Released:2021-06-04)
参考文献数
19
被引用文献数
8

There is a worldwide attempt to develop prevention strategies against SARS-CoV-2 transmission. Here we examined the effectiveness of tungsten trioxide (WO3)-based visible light-responsive photocatalyst on the inactivation of SARS-CoV-2 under different temperatures and exposure durations. The viral titer on the photocatalyst-coated glass slides decreased from 5.93 ± 0.38 logTCID50 /mL to 3.05 ±. 25 logTCID50/mL after exposure to 3,000 lux of the visible light irradiation for 6h at 20℃. On the other hand, lighting without the photocatalyst, or the photocatalyst-coat without lighting retained viral stability. Immunoblotting and electron microscopic analyses showed the reduced amounts of spike protein on the viral surface after the photocatalyst treatment. Our data suggest a possible implication of the photocatalyst on the decontamination of SARS-CoV-2 in indoor environments, thereby preventing indirect viral spread.