- 著者
- Masayoshi Furushiro Satoru Suzuki Yoshiyuki Shishido Masashi Sakai Hideyuki Yamatoya Satoshi Kudo Shusuke Hashimoto Teruo Yokokura
- 出版者
- The Japanese Pharmacological Society
- 雑誌
- The Japanese Journal of Pharmacology (ISSN:00215198)
- 巻号頁・発行日
- vol.75, no.4, pp.447-450, 1997 (Released:2006-03-27)
- 参考文献数
- 15
- 被引用文献数
- 20 21
Soybean lecithin transphosphatidylated phosphatidylserine (SB-tPS) was investigated for its effect on the impaired learning of a passive avoidance task by mice induced by scopolamine or cycloheximide. SB-tPS (240, 360, 480 mg/kg) administered orally significantly prolonged the step-through latency shortened by scopolamine. SB-tPS (240 mg/kg) administered orally also prolonged the step-through latency shortened by cycloheximide. These results suggest that the effect of SB-tPS on the impaired learning behavior may be related not only to the cholinergic system but also the serotonergic system.