著者

JUNICHI AZUMA AKIHIKO SAWAMURA NOBUHISA AWATA

出版者

The Japanese Circulation Society

雑誌

JAPANESE CIRCULATION JOURNAL (ISSN:00471828)

巻号頁・発行日

vol.56, no.1, pp.95-99, 1992-01-20 (Released:2008-04-14)

参考文献数

30

被引用文献数

95 117

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We compared the effect of oral administration of taurine (3g/day) and coenzyme Q10 (CoQ<>) (30 mg/day) in 17 patients with congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy, whose ejection fraction assessed by echocardiography was less than 50%. The changes in echo-cardiographic parameters produced by 6 weeks of treatment were evaluated in a double-blind fashion. In the taurine-treated group significant treatment effect was observed on systolic left ventricular function after 6 weeks. Such an effect was not observed in the CoQ10-treated group.