- 著者
-
Tetsuaki Ban
Shin-ichiro Fujiwara
Rui Murahashi
Hirotomo Nakajima
Takashi Ikeda
Sae Matsuoka
Yumiko Toda
Shin-ichiro Kawaguchi
Shoko Ito
Takashi Nagayama
Kento Umino
Daisuke Minakata
Hirofumi Nakano
Kaoru Morita
Masahiro Ashizawa
Chihiro Yamamoto
Kaoru Hatano
Kazuya Sato
Ken Ohmine
Yoshinobu Kanda
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.61, no.7, pp.989-995, 2022-04-01 (Released:2022-04-01)
- 参考文献数
- 19
- 被引用文献数
-
3
Objective Peripherally inserted central catheters (PICCs) are widely used in patients with hematologic malignancies. However, the risks of PICC-related complications during chemotherapy for acute myeloid leukemia (AML) are not fully understood. Methods We conducted a retrospective review of 128 adult patients with AML who received induction therapy by way of PICC insertion between 2012 and 2019. Results The median duration of PICC insertion was 30 days. The incidence rate of catheter-related bloodstream infection (CRBSI) was 2.4% at 30 days, and women were more likely to suffer from CRBSI than men. Local reactions at the insertion site were observed in 56 patients; however, these events did not predict CRBSI. The incidence rates of catheter-related thrombosis (CRT) were 1.6% at 30 days. Obesity put patients at an increased risk for CRT. Unexpected PICC removal occurred in 59 patients, and women were at a higher risk of catheter removal than men. Conclusion Low PICC-related complication rates, possibly associated with high rates of catheter removal, were observed during intensive chemotherapy for AML. Women and obese patients require careful monitoring of their PICC. Procedures to achieve appropriate PICC removal without increasing the complication rate need to be considered.