- 著者
-
Akitake Suzuki
Naoki Asazuma
Eigo Kikuchi
Takeshi Kawanobe
Yoshihiko Horimoto
Ryuichi Yokobari
Shigeru Kotake
Takahiro Okai
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.51, no.7, pp.813-816, 2012 (Released:2012-04-01)
- 参考文献数
- 9
- 被引用文献数
-
10
10
4
Although antiphospholipid antibody syndrome (APS) is an autoimmune condition that is primarily characterized by arterial or venous thrombosis or pregnancy morbidity and the presence of antiphospholipid antibodies (aPL), recent reviews have introduced non-thromboembolic manifestations. We describe the case of a 58-year-old woman with vegetation on the aortic valve, whose initial presentation of APS abruptly developed into diffuse pulmonary hemorrhage. Despite consecutive plasma exchange procedures and the administration of corticosteroids and high-dose intravenous immunoglobulin, multiple brain infarctions developed, and the patient died of pneumonia. Although anecdotal, this case might serve as a useful example of the non-standard complications of fulminant APS.