3 0 0 0 OA Evolving genetic code
- 著者
- Takeshi OHAMA Yuji INAGAKI Yoshitaka BESSHO Syozo OSAWA
- 出版者
- The Japan Academy
- 雑誌
- Proceedings of the Japan Academy, Series B (ISSN:03862208)
- 巻号頁・発行日
- vol.84, no.2, pp.58-74, 2008-02-28 (Released:2008-02-12)
- 参考文献数
- 47
- 被引用文献数
- 17 23
In 1985, we reported that a bacterium, Mycoplasma capricolum, used a deviant genetic code, namely UGA, a “universal” stop codon, was read as tryptophan. This finding, together with the deviant nuclear genetic codes in not a few organisms and a number of mitochondria, shows that the genetic code is not universal, and is in a state of evolution. To account for the changes in codon meanings, we proposed the codon capture theory stating that all the code changes are non-disruptive without accompanied changes of amino acid sequences of proteins. Supporting evidence for the theory is presented in this review. A possible evolutionary process from the ancient to the present-day genetic code is also discussed.(Communicated by Takao SEKIYA, M.J.A.)
1 0 0 0 OA Silent evolution
- 著者
- Syozo OSAWA Zhi-Hui SU Masaaki NISHIKAWA Osamu TOMINAGA
- 出版者
- The Japan Academy
- 雑誌
- Proceedings of the Japan Academy, Series B (ISSN:03862208)
- 巻号頁・発行日
- vol.92, no.9, pp.455-461, 2016-11-11 (Released:2016-11-11)
- 参考文献数
- 16
- 被引用文献数
- 1
Phylogenetic analyses using mitochondrial DNA sequences of several kinds of beetles have shown that their evolution included a silent stage in which no morphological changes took place. We thus propose a new category of evolutionary process called “silent evolution”.