著者
HIDEO INOUE TOHRU UEDA
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
vol.19, no.8, pp.1743-1744, 1971-08-25 (Released:2011-02-08)
参考文献数
10
被引用文献数
12 17
著者
YUKARI SUZUKI AKIRA MATSUDA TOHRU UEDA
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
vol.35, no.5, pp.1808-1811, 1987-05-25 (Released:2009-10-19)
参考文献数
7
被引用文献数
10 10

Oxidation of 6, 5'-cyclo-5'-deoxy-2', 3'-Ο-isopropylideneuridine with selenium dioxide gave the 5'-oxo derivative, which was converted to the 5'-ethoxycarbonylmethylidene derivative (3). Reduction of 3 afforded, after deprotection, the title compounds (6, R and S). The base-catalyzed epimerization of 6 at the 5'-position was observed, and the equilibrium was in favor of the (R) -epimer.