著者
Takuma Tsukioka Kiyotoshi Inoue Hiroko Oka Shinjiro Mizuguchi Ryuhei Morita Noritoshi Nishiyama
出版者
The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery
雑誌
Annals of Thoracic and Cardiovascular Surgery (ISSN:13411098)
巻号頁・発行日
pp.oa.12.01986, (Released:2012-12-26)
参考文献数
12
被引用文献数
7 12

Purpose: Pleurodesis continues to play a central role in the management of pneumothorax. In our institute, a 50% glucose solution is used for pleurodesis. We retrospectively analysed the treatment effects of pleurodesis in patients with spontaneous pneumothorax in whom an operation was contraindicated because of underlying disease.Methods: 13 patients (18 cases) with spontaneous pneumothorax were treated with pleurodesis with a 50% glucose solution. After local anesthesia of parietal pleura, 200 to500 mL of a 50% glucose solution was instilled into the pleural space. Pleurodesis was repeated two or three times, until the air leakage stopped.Results: Air leakage stopped in all cases and there were no treatment-related deaths.Overall survival rates at 1, 2, and 3 years after treatment were 83%, 74%, and 49%, respectively. Post-treatment recurrence was observed in six cases. Four cases of recurrence were treated with pleurodesis with a 50% glucose solution. All cases of recurrence occurred within 3 months after pleurodesis.Conclusion: Pleurodesis with a 50% glucose solution is effective and safe in patients with pneumothorax. This procedure can be performed in patients with recurrent pneumothorax as well as patients with a first episode of pneumothorax in whom prolonged air leakage is predicted.