著者

Jin Imai Takayoshi Suzuki Marie Yoshikawa Makiko Dekiden Hirohiko Nakae Fumio Nakahara Shingo Tsuda Hajime Mizukami Jun Koike Muneki Igarashi Hiromasa Yabe Tetsuya Mine

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.55, no.23, pp.3441-3444, 2016-12-01 (Released:2016-12-01)

参考文献数

20

被引用文献数

5

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Dyskeratosis congenita (DC) is a rare inherited disease in which the telomere complex cannot be maintained. Shortened telomeres can cause a number of clinical conditions. We herein report a case of unrelated bone marrow transplantation due to aplastic anemia associated with DC. The patient died of uncontrollable refractory intestinal bleeding. Three cases of DC with life-threatening hemorrhaging after transplantation have been reported; however, the bleeding origin could not be determined. Our case is the only patient in which a gastrointestinal bleeding point, jejunal multiple angioectasia, was determined.